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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">avk</journal-id><journal-title-group><journal-title xml:lang="ru">Архивъ внутренней медицины</journal-title><trans-title-group xml:lang="en"><trans-title>The Russian Archives of Internal Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2226-6704</issn><issn pub-type="epub">2411-6564</issn><publisher><publisher-name>“SINAPS” LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20514/2226-6704-2020-10-5-357-371</article-id><article-id custom-type="elpub" pub-id-type="custom">avk-1089</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLE</subject></subj-group></article-categories><title-group><article-title>Компьютерная томография при коронавирусной инфекции: дифференциальный диагноз на клинических примерах</article-title><trans-title-group xml:lang="en"><trans-title>The Role of Computed Tomography in Differentiation of Coronavirus Pneumonia, its Complications and Comorbidities. Case Reports</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Петровичев</surname><given-names>В. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Petrovichev</surname><given-names>V. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1637-2402</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мелехов</surname><given-names>А. .В.</given-names></name><name name-style="western" xml:lang="en"><surname>Melekhov</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Александр Всеволодович Мелехов</p><p>Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><email xlink:type="simple">avmelekhov@gmail.com</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сайфуллин</surname><given-names>М. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Sayfullin</surname><given-names>M. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Никитин</surname><given-names>И. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Nikitin</surname><given-names>I. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГАУ «НМИЦ Лечебно-реабилитационный центр» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>National Medical Research Center of Treatment and Rehabilitation of the Russian Healthcare Ministry</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГАУ «НМИЦ Лечебно-реабилитационный центр» Минздрава России; ФГАОУ ВО «РНИМУ имени Н.И. Пирогова» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>National Medical Research Center of Treatment and Rehabilitation of the Russian Healthcare Ministry; Pirogov Russian National Research Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ФГАУ «НМИЦ Лечебно-реабилитационный центр» Минздрава России; ФГАОУ ВО «РНИМУ имени Н.И. Пирогова» Минздрава России; ФГБУ «Национальный исследовательский центр эпидемиологии и микробиологии имени почетного академика Н.Ф. Гамалеи» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>National Medical Research Center of Treatment and Rehabilitation of the Russian Healthcare Ministry; Pirogov Russian National Research Medical University; Gamaleya National Research Center for Epidemiology and Microbiology of the Russian Healthcare Ministry</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2020</year></pub-date><pub-date pub-type="epub"><day>08</day><month>10</month><year>2020</year></pub-date><volume>10</volume><issue>5</issue><fpage>357</fpage><lpage>371</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Петровичев В.С., Мелехов А..., Сайфуллин М.А., Никитин И.Г., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Петровичев В.С., Мелехов А..., Сайфуллин М.А., Никитин И.Г.</copyright-holder><copyright-holder xml:lang="en">Petrovichev V.S., Melekhov A.V., Sayfullin M.A., Nikitin I.G.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.medarhive.ru/jour/article/view/1089">https://www.medarhive.ru/jour/article/view/1089</self-uri><abstract><sec><title> </title><p> </p></sec><sec><title>Введение</title><p>Введение: большое количество литературы посвящено дифференциальному диагнозу рентгенологических симптомов COVID-19, их отличиям от других вариантов легочного поражения (другие вирусные и бактериальные пневмонии), не-легочных заболеваний. В реальной клинической практике коронавирусная пневмония может развиваться у пациентов, имеющих рентгенологические признаки и другого, интеркурентного заболевания.</p></sec><sec><title>Цель</title><p>Цель: изучение частоты и особенностей рентгенологических проявлений коронавирусной инфекции, ее осложнений и сопутствующих заболеваний органов грудной клетки.</p></sec><sec><title>Методы</title><p>Методы: ретроспективный анализ рентгенологических и клинических данных 354 пациентов, госпитализированных в ФГАУ «НМИЦ Лечебно-реабилитационный центр» Минздрава России с подозрением на коронавирусную инфекцию в период апрель-май 2020 г.</p></sec><sec><title>Результаты</title><p>Результаты: Проанализировано 962 исследования (3 (2-3) исследования на пациента). Первое КТ исследование проводилось пациентам на 8 (5-11) день болезни. На основании выявляемых рентгенологических симптомов выделено несколько групп пациентов: с коронавирусной пневмонией (n=295; 83%); с сочетанием коронавирусной пневмонии и другого заболевания (n=36; 10%); с осложнениями COVID-19 (n=12; 3%); с альтернативной патологией (n=2; 1%); без патологии (n=9; 3%). Приведены клинические случаи пациентов, демонстрирующие различные клинико-рентгенологические сценарии.</p></sec><sec><title>Заключение</title><p>Заключение: В клинической практике, помимо выявления типичных для COVID-19 изменений, метод КТ позволял проводить дифференциальную диагностику легочной и внелегочной патологией у коморбидных больных.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Background</title><p>Background: computer tomography (CT) features of COVID-19, their temporal changes and differences from other pulmonary (viral and bacterial pneumonia) and non-pulmonary diseases are well described in recent publications. The prevalence and characteristics of signs of concomitant problems that could be identified at chest CT are less studied.</p></sec><sec><title>Aim</title><p>Aim: to analyze the prevalence and characteristics of chest CT features of COVID-19, its complications and comorbidities.</p></sec><sec><title>Methods</title><p>Methods: retrospective analysis of CT and clinical data of 354 patients hospitalized with suspected COVID at April and May of 2020.</p></sec><sec><title>Results</title><p>Results: 962 CT scans were analyzed (3 (2-3) scans per patient). First CT was performed at 8 (5-11) day of sickness. Several roentgenological scenarios could be highlighted: patients with coronavirus pneumonia (n=295; 83%); with combination of COVID-19 and another pathology (n=36; 10%); with complications of COVID-19 (n=12; 3%); with alternative pathology (n=2; 1%); without any pathological signs (n=9; 3%). Several cases, illustrating CT signs of coronavirus pneumonia, its complications and comorbidities are reported.</p></sec><sec><title>Conclusion</title><p>Conclusion: CT possibilities are not limited to detect typical COVID-19 signs, it also helps to differentiate pulmonary and other thoracis pathology.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>COVID-19</kwd><kwd>коронавирусная пневмония</kwd><kwd>мультиспиральная компьютерная томография</kwd><kwd>дифференциальный диагноз</kwd></kwd-group><kwd-group xml:lang="en"><kwd>COVID-19</kwd><kwd>coronavirus pneumonia</kwd><kwd>multispiral computed tomography</kwd><kwd>differentiation of complications and comorbidities</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Undiagnosed pneumonia — China (Hubei): request for information. [Электронный ресурс]. URL: https://promedmail.org/promedpost/?id=6864153. 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