avkАрхивъ внутренней медициныThe Russian Archives of Internal Medicine2226-67042411-6564“SINAPS” LLC10.20514/2226-6704-2021-11-2-111-121avk-1171Research ArticleОБЗОРНЫЕ СТАТЬИREVIEW ARTICLESМесто пациентов с промежуточной фракцией выброса левого желудочка в общей популяции больных хронической сердечной недостаточностьюPosition of Patients with Mid-Range Ejection Fraction in the General Chronic Heart Failure Populationhttps://orcid.org/0000-0003-4307-1522ВатутинН. Т.VatutinN. T.

Донецк

Donetsk

https://orcid.org/0000-0001-6192-2576ШевелёкА. Н.ShevelokA. N.

Донецк

Donetsk

ВенжегаВ. В.VenzhehaV. V.

Виктория Валериевна Венжега

Москва

Moscow

vika2864@yandex.ruГОО ВПО «Донецкий национальный медицинский университет им. М. Горького»; Институт неотложной и восстановительной хирургии им. В.К. ГусакаУкраинаState Educational Organization of Higher Professional Education «M. Gorky Donetsk National Medical University»; V.K. Gusak Institute of emergency and reconstructive surgeryUkraineФГАОУ ВО «Российский национальный исследовательский медицинский университет имени Н.И. Пирогова» Министерства Здравоохранения Российской ФедерацииРоссияFederal state Autonomous educational institution of higher education «Pirogov Russian National Research Medical University» Russian Federation Department of HealthRussian Federation202130032021112111121Copyright © Ватутин Н.Т., Шевелёк А.Н., Венжега В.В., 20212021Ватутин Н.Т., Шевелёк А.Н., Венжега В.В.Vatutin N.T., Shevelok A.N., Venzheha V.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.medarhive.ru/jour/article/view/1171

В 2016г в рекомендациях Европейского общества кардиологов по диагностике и лечению острой и хронической сердечной недостаточности (ХСН) выделена новая группа пациентов с промежуточной фракцией выброса левого желудочка (пФВ ЛЖ), референтный интервал которой лежит в диапазоне 40-49 %. В представленном обзоре освещены вопросы эпидемиологии, этиологии и диагностики ХСНпФВ, профиль биомаркеров и динамические фенотипы пациентов, рассмотрены принципы лечения и факторы, определяющие прогноз заболевания. Особое внимание уделено особенностям формирования разнородной когорты пациентов и целесообразности расширения существующей на сегодняшний день классификации ХСНпФВ путем введения двух переходных фенотипов.

The European society of cardiology guideline for the diagnosis and treatment of acute and chronic heart failure (CHF) in 2016 identified a new group of patients with mid-range left ventricular ejection fraction (LVEF) with reference interval in the range of 40-49 %. This review highlights the issues of epidemiology and etiology of CHF, outlines the echocardiographic portrait, biomarker profile and patients` dynamic phenotypes, considers the guidelines of their managements and the prognosis of the disease determiner’s factors. Special attention is paid to the peculiarities of the formation of this heterogeneous cohort of patients and the feasibility of expanding the existing CHF classification by introducing two transitional phenotypes.

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The authors declare that there are no conflicts of interest present.