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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">avk</journal-id><journal-title-group><journal-title xml:lang="ru">Архивъ внутренней медицины</journal-title><trans-title-group xml:lang="en"><trans-title>The Russian Archives of Internal Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2226-6704</issn><issn pub-type="epub">2411-6564</issn><publisher><publisher-name>“SINAPS” LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20514/2226-6704-2021-11-6-466-471</article-id><article-id custom-type="elpub" pub-id-type="custom">avk-1338</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>РАЗБОР КЛИНИЧЕСКИХ СЛУЧАЕВ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ANALYSIS OF CLINICAL CASES</subject></subj-group></article-categories><title-group><article-title>Клинический случай диагностики апластической анемии после перенесенной инфекции COVID-19</article-title><trans-title-group xml:lang="en"><trans-title>A Clinical Case of Aplastic Anemia After COVID-19 Infection</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2627-0626</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сафуанова</surname><given-names>Г. Ш.</given-names></name><name name-style="western" xml:lang="en"><surname>Safuanova</surname><given-names>G. Sh.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Гузяль Шагбановна Сафуанова</p><p>Уфа</p></bio><bio xml:lang="en"><p>Guzyal Sh. Safuanova</p><p>Ufa</p><p>Moscow</p></bio><email xlink:type="simple">safuanova@bk.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Константинова</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Константинова</surname><given-names>А. С.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Уфа</p></bio><bio xml:lang="en"><p>Ufa</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Латыпова</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Latypova</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Уфа</p></bio><bio xml:lang="en"><p>Ufa</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Багаутдинова</surname><given-names>А. У.</given-names></name><name name-style="western" xml:lang="en"><surname>Bagautdinova</surname><given-names>A. U.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Уфа</p></bio><bio xml:lang="en"><p>Ufa</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сафуанова</surname><given-names>Д. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Safuanova</surname><given-names>D. R.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Кафедра терапии и общей врачебной практики с курсом гериатрии ИДПО, Федеральное государственное бюджетное образовательное учреждение высшего образования «Башкирский государственный медицинский университет» Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Department of Therapy and General Medical Practice with a Course of Geriatrics. Federal State Budgetary Educational Institution of Higher Education «Bashkir State Medical University» of the Ministry of Healthcare of the Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Государственное бюджетное учреждение здравоохранения «Республиканская клиническая больница им. Г.Г. Куватова» Министерства здравоохранения Республики Башкортостан</institution><country>Россия</country></aff><aff xml:lang="en"><institution>State Budgetary Healthcare Institution «Kuvatov Republican Clinical Hospital» of the Ufa Healthcare Department</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Федеральное государственное бюджетное образовательное учреждение высшего образования «Первый московский медицинский университет им И.М. Сеченова» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal State Budgetary Educational Institution of Higher Education «I.M. Sechenov First Moscow Medical University», Ministry of Healthcare of the Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>29</day><month>11</month><year>2021</year></pub-date><volume>11</volume><issue>6</issue><fpage>466</fpage><lpage>471</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Сафуанова Г.Ш., Константинова А.С., Латыпова А.А., Багаутдинова А.У., Сафуанова Д.Р., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Сафуанова Г.Ш., Константинова А.С., Латыпова А.А., Багаутдинова А.У., Сафуанова Д.Р.</copyright-holder><copyright-holder xml:lang="en">Safuanova G.S., Константинова А.С., Latypova A.A., Bagautdinova A.U., Safuanova D.R.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.medarhive.ru/jour/article/view/1338">https://www.medarhive.ru/jour/article/view/1338</self-uri><abstract><p>Апластическая анемия — редкое заболевание системы крови, для которого характерно угнетение кроветворения во всех линиях гемопоэза, замещение кроветворной ткани на жировую и отсутствие других причин или заболеваний, которые могут подавлять гемопоэз. Частота заболеваемости составляет 2-3 случая на 1 млн населения в год в регионах Европы и Америки, показатели в 2-3 раза выше в Восточной Азии. Чаще заболевание начинается в возрастном промежутке от 10 до 25 лет и старше 60 лет. Этиология в 70-80 % случаях остается неизвестной. Частота приобретенных случаев заболевания преобладает над врожденными. Провоцирующими факторами могут быть химическое, физическое воздействие, лекарственные препараты, вирусные инфекции. В данной работе описан случай развития апластической анемии у пациентки после принесенной коронавирусной инфекции.</p></abstract><trans-abstract xml:lang="en"><p>Aplastic anemia is a rare disease of the blood system characterized by suppression of hematopoiesis in all lines of hematopoiesis, replacement of hematopoietic tissue with fatty tissue and absence of other causes or diseases that can suppress hematopoiesis. The incidence is 2-3 cases per 1 million population per year in the regions of Europe and America, rates are 2-3 times higher in East Asia. The disease most often begins between the ages of 10 and 25 years and over 60 years. The etiology remains unknown in 70-80 % of cases. The frequency of acquired cases predominates over congenital cases. The triggering factors can be chemical, physical exposures, medications, and viral infections. This case report describes a case of a patient developing aplastic anemia, as a result of a coronavirus infection.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>апластическая анемия</kwd><kwd>панцитопения</kwd><kwd>аутоиммунные заболевания</kwd><kwd>COVID-19</kwd><kwd>коронавирусная инфекция</kwd></kwd-group><kwd-group xml:lang="en"><kwd>aplastic anemia</kwd><kwd>pancytopenia</kwd><kwd>autoimmune disease</kwd><kwd>COVID-19</kwd><kwd>coronavirus infection</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Novelli L., Motta F., De Santis M. et al. The JANUS of chronic inflammatory and autoimmune diseases onset during COVID-19 — A systematic review of the literature. J Autoimmun. 2021; 117: 102592. doi: 10.1016/j.jaut.2020.102592. 2020.</mixed-citation><mixed-citation xml:lang="en">Novelli L., Motta F., De Santis M. et al. 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