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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">avk</journal-id><journal-title-group><journal-title xml:lang="ru">Архивъ внутренней медицины</journal-title><trans-title-group xml:lang="en"><trans-title>The Russian Archives of Internal Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2226-6704</issn><issn pub-type="epub">2411-6564</issn><publisher><publisher-name>“SINAPS” LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20514/2226-6704-2022-12-1-22-34</article-id><article-id custom-type="elpub" pub-id-type="custom">avk-1371</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEW ARTICLES</subject></subj-group></article-categories><title-group><article-title>Периоперационное ведение пациентов с ревматологическими заболеваниями: рекомендации по применению глюкокортикостероидов, болезнь-модифицирующих антиревматических препаратов, генно-инженерных биологических препаратов, нестероидных противовоспалительных препаратов</article-title><trans-title-group xml:lang="en"><trans-title>Perioperative Management of Patients with Rheumatic Diseases: Glucocorticoids, DMARDs, Biological Agents and NSAIDs</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4262-4060</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лялина</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Lyalina</surname><given-names>V. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Вера Валерьевна Лялина</p><p>Москва</p></bio><bio xml:lang="en"><p>Vera V. Lyalina</p><p>Moscow</p></bio><email xlink:type="simple">vera_lyalina@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9365-1472</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Борисовская</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Borisovskaya</surname><given-names>S. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6321-8419</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Скрипниченко</surname><given-names>Э. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Skripnichenko</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1237-3731</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Эттингер</surname><given-names>О. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Ettinger</surname><given-names>O. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0877-9672</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Паджева</surname><given-names>Т. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Padzheva</surname><given-names>T. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1699-0881</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Никитин</surname><given-names>И. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Nikitin</surname><given-names>I. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><xref ref-type="aff" rid="aff-4"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Кафедра госпитальной терапии № 2 ЛФ ФГАОУ ВО РНИМУ им. Н. И. Пирогова Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Pirogov Russian National Research Medical University (Pirogov Medical University)</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Кафедра госпитальной терапии № 2 ЛФ ФГАОУ ВО РНИМУ им. Н. И. Пирогова Минздрава России; ГБУЗ «ГКБ имени В. М. Буянова ДЗМ»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Pirogov Russian National Research Medical University (Pirogov Medical University); Buyanov City Clinical Hospital</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ГБУЗ «ГКБ № 40 ДЗМ»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Moscow City Clinical Hospital № 40</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>Кафедра госпитальной терапии № 2 ЛФ ФГАОУ ВО РНИМУ им. Н. И. Пирогова Минздрава России; ФГАУ «НМИЦ «ЛРЦ» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Pirogov Russian National Research Medical University (Pirogov Medical University); National Medical Research Center of Treatment and Rehabilitation</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>31</day><month>01</month><year>2022</year></pub-date><volume>12</volume><issue>1</issue><fpage>22</fpage><lpage>34</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Лялина В.В., Борисовская С.В., Скрипниченко Э.А., Эттингер О.А., Паджева Т.М., Никитин И.Г., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Лялина В.В., Борисовская С.В., Скрипниченко Э.А., Эттингер О.А., Паджева Т.М., Никитин И.Г.</copyright-holder><copyright-holder xml:lang="en">Lyalina V.V., Borisovskaya S.V., Skripnichenko E.A., Ettinger O.A., Padzheva T.M., Nikitin I.G.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.medarhive.ru/jour/article/view/1371">https://www.medarhive.ru/jour/article/view/1371</self-uri><abstract><p>Пациенты с ревматологическими заболеваниями характеризуются рядом особенностей, которые необходимо учитывать в процессе периоперационного ведения. В частности, ревматологические заболевания приводят к двигательным ограничениям, нарушению структуры и снижению функции многих органов и систем, необходимости постоянного приёма иммуносупрессивных и других лекарствен ных средств. В связи с этим у пациентов отмечается повышенный риск разнообразных интраоперационных и послеоперационных осложнений. Целью данной публикации является рассмотрение современных рекомендаций по периоперационному ведению пациентов с ревматологическими заболеваниями. В данной публикации рассматривается один из наиболее сложных вопросов — периоперационное применение лекарственных препаратов: глюкокортикостероидов, базисных болезнь-модифицирующих антиревматических препаратов, генно-инженерных биологических препаратов и нестероидных противовоспалительных препаратов.</p></abstract><trans-abstract xml:lang="en"><p>The rheumatic patients are characterized by various structural and functional changes, caused by chronic disease the necessity of constant medication intake, including anti-inflammatory drugs and immunosuppressants. In this regard, the rheumatic patients have an increased risk of intraoperative and postoperative complications. The purpose of this publication is to review current recommendations on the topic of perioperative management of rheumatic patients. The publication consists of two parts. In the first part we review the issues of perioperative administration of steroids, disease-modifying antirheumatic drugs, biologics and nonsteroidal anti-inflammatory drugs.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>ревматоидный артрит</kwd><kwd>периоперационное ведение</kwd><kwd>базисные болезнь-модифицирующие антиревматические препараты</kwd><kwd>БМАРП</kwd><kwd>метотрексат</kwd><kwd>генно-инженерные биологические препараты</kwd><kwd>системная красная волчанка</kwd><kwd>глюкокортикостероиды</kwd><kwd>ГКС</kwd></kwd-group><kwd-group xml:lang="en"><kwd>rheumatoid arthritis</kwd><kwd>perioperative management</kwd><kwd>perioperative care</kwd><kwd>disease-modifying anti-rheumatic drug</kwd><kwd>methotrexate</kwd><kwd>biological agents</kwd><kwd>systemic lupus erythematosus</kwd><kwd>glucocorticoids</kwd><kwd>surgical intervention</kwd><kwd>NSAIDs</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Goodman S.M., Springer B., Guyatt G. et al. 2017 American College of Rheumatology/American Association of Hip and Knee Surgeons Guideline for the Perioperative Management of Antirheumatic Medication in Patients With Rheumatic Diseases Undergoing Elective Total Hip or Total Knee Arthroplasty. 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