<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">avk</journal-id><journal-title-group><journal-title xml:lang="ru">Архивъ внутренней медицины</journal-title><trans-title-group xml:lang="en"><trans-title>The Russian Archives of Internal Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2226-6704</issn><issn pub-type="epub">2411-6564</issn><publisher><publisher-name>“SINAPS” LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20514/2226-6704-2021-12-2-156-160</article-id><article-id custom-type="elpub" pub-id-type="custom">avk-1409</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>РАЗБОР КЛИНИЧЕСКИХ СЛУЧАЕВ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ANALYSIS OF CLINICAL CASES</subject></subj-group></article-categories><title-group><article-title>Случай полной АВ-блокады у пациента с клещевым боррелиозом</article-title><trans-title-group xml:lang="en"><trans-title>A Case of Complete AV Blockade in Patient with Lyme Borreliosis</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2216-5490</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Денисов</surname><given-names>О. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Denisov</surname><given-names>O. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ульяновск</p></bio><bio xml:lang="en"><p>Ulyanovsk </p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7579-4824</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ефремова</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Efremova</surname><given-names>E. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ульяновск</p></bio><bio xml:lang="en"><p>Ulyanovsk </p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3113-6018</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Нафеев</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Nafeev</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ульяновск</p></bio><bio xml:lang="en"><p>Ulyanovsk</p></bio><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГУЗ «Ульяновская областная клиническая больница»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Ulyanovsk Regional Clinical Hospital</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБОУ ВО «Ульяновский государственный университет»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Ulyanovsk State University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ФБУЗ «Центр гигиены и эпидемиологии в Ульяновской области»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Center for Hygiene and Epidemiology in the Ulyanovsk Region</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>30</day><month>03</month><year>2022</year></pub-date><volume>12</volume><issue>2</issue><fpage>156</fpage><lpage>160</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Денисов О.Н., Ефремова Е.В., Нафеев А.А., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Денисов О.Н., Ефремова Е.В., Нафеев А.А.</copyright-holder><copyright-holder xml:lang="en">Denisov O.N., Efremova E.V., Nafeev A.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.medarhive.ru/jour/article/view/1409">https://www.medarhive.ru/jour/article/view/1409</self-uri><abstract><p>Болезнь Лайма (клещевой боррелиоз) — инфекционное трансмиссивное природно-очаговое заболевание, имеющее наклонность к хроническому и рецидивирующему течению с преимущественным поражением кожи, нервной системы, опорно-двигательного аппарата и сердца. Миокардиальное повреждение проявляется, как правило, поражением проводящей системы в виде атриовентрикулярной блокады различной степени, внутрижелудочковой блокады, дисфункции синоатриального узла. При несвоевременной диагностике и отсутствии этиотропного лечения клещевого боррелиоза может возникнуть хронизация поражения проводящей системы сердца и потребоваться имплантация электрокардиостимулятора.</p></abstract><trans-abstract xml:lang="en"><p>Lyme disease (tick-borne borreliosis) is an infectious vector-borne natural focal disease that tends to a chronic and recurrent course with a predominant damage to the skin, nervous system, musculoskeletal system and heart. Cardiac features is manifested, as a rule, by a involvement of the conducting system as varying degrees of atrioventricular block, Bundle–branch block, dysfunction of the sinoatrial node. In case of untimely diagnosis and etiotropic treatment of tick-borne borreliosis, chronic lesions of the cardiac conduction system may occurs and implantation of a pacemaker may be required.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>болезнь Лайма</kwd><kwd>атриовентрикулярная блокада</kwd><kwd>клинический случай</kwd></kwd-group><kwd-group xml:lang="en"><kwd>Lyme disease</kwd><kwd>atrioventricular block</kwd><kwd>clinical case</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Международная ассоциация специалистов в области инфекций. Клинические рекомендации «Болезнь Лайма у взрослых» (утв. Минздравом России). 2016: 24 с.</mixed-citation><mixed-citation xml:lang="en">International Association for Infection Specialists. Clinical guidelines «Lyme disease in adults» (approved by the Ministry of Health of Russia). 2016: 24 р. [in Russian]</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Bush L.M., Vazquez-Pertejo M. T: Tick borne illness—Lyme disease. Dis Mon. 2018; 64(5): 195-212. doi: 10.1016/j.disamonth.2018.01.007.</mixed-citation><mixed-citation xml:lang="en">Bush L.M., Vazquez-Pertejo M. T: Tick borne illness—Lyme disease. Dis Mon. 2018; 64(5): 195-212. doi: 10.1016/j.disamonth.2018.01.007.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Dubrey S.W., Mehta P.A., O’Connell S. Lyme disease and the heart in the UK. Br J Hosp Med (Lond). 2011; 72(11): 621-25. doi: 10.12968/hmed.2011.72.11.621.</mixed-citation><mixed-citation xml:lang="en">Dubrey S.W., Mehta P.A., O’Connell S. Lyme disease and the heart in the UK. Br J Hosp Med (Lond). 2011; 72(11): 621-25. doi: 10.12968/hmed.2011.72.11.621.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Yeung C., Baranchuk, A. Diagnosis and Treatment of Lyme Carditis. Journal of the American College of Cardiology. 2019; 73(6): 717–726. doi:10.1016/j.jacc.2018.11.035.</mixed-citation><mixed-citation xml:lang="en">Yeung C., Baranchuk, A. Diagnosis and Treatment of Lyme Carditis. Journal of the American College of Cardiology. 2019; 73(6): 717–726. doi:10.1016/j.jacc.2018.11.035.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Лыгина Е.В., Мирошкин С.В. Клинический случай иксодового клещевого боррелиоза с развитием A-V блокады и имплантацией электрокардиостимулятора. Российский медико-биологический вестник имени академика И.П. Павлова. 2017; 25(4): 586-592. doi: 10.23888/PAVLOVJ20174586-598.</mixed-citation><mixed-citation xml:lang="en">Lygina E.V., Miroshkin S.V. Clinical case of ixodic tick-borne borreliosis with the development of A-V blockade and implantation of a pacemaker. Russian medical and biological bulletin named after academician I.P. Pavlova. 2017; 25(4): 586-592. doi: 10.23888/PAVLOVJ20174586-598. [in Russian]</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Van der Linde M.R., Crijns H.J., de Koning J. et al. Range of atrioventricular conduction disturbances in Lyme borreliosis: a report of our cases and review of other published reports. Br Heart J.1990; 63(3): 162–8. doi: 10.1136/hrt.63.3.162.</mixed-citation><mixed-citation xml:lang="en">Van der Linde M.R., Crijns H.J., de Koning J. et al. Range of atrioventricular conduction disturbances in Lyme borreliosis: a report of our cases and review of other published reports. Br Heart J.1990; 63(3): 162–8. doi: 10.1136/hrt.63.3.162.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Нафеев А.А., Бергельсон Т.М., Нафеева А.А. Эпидемиологические черты иксодового клещевого боррелиоза у детей в Ульяновской области. Детские инфекции. 2019; 18(4): 53-55. doi:10.22627/2072-8107-2019-18-4-53-55.</mixed-citation><mixed-citation xml:lang="en">Nafeev A.A., Bergelson T.M., Nafeeva A.A. Epidemiological features of Ixodic tick-borne Borreliosis in children in the Ulyanovsk region Childhood infections. 2019; 18(4): 53-55. doi:10.22627/2072-8107-2019-18-4-53-55. [in Russian]</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Базарный В.В., Корикова М.Ю., Волкова Л.И. и др. Оптимизация серологической диагностики Лайм-боррелиоза. Клиническая лабораторная диагностика. 2003; 12: 49-50.</mixed-citation><mixed-citation xml:lang="en">Bazarniy V.V., Korikova M.Yu., Volkovа L.I. et al. Optimization of serological diagnosis of Lyme borreliosis. Clinical Laboratory Diagnostics. 2003; 12: 49-50. [in Russian]</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Costello J.M., Alexander M.E., Greco K.M. et al Lyme carditis in children: presentation, predictive factors, and clinical course. Pediatrics. 2009; 123(5): e835–841. doi: 10.1542/peds.2008-3058.</mixed-citation><mixed-citation xml:lang="en">Costello J.M., Alexander M.E., Greco K.M. et al Lyme carditis in children: presentation, predictive factors, and clinical course. Pediatrics. 2009; 123(5): e835–841. doi: 10.1542/peds.2008-3058.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Stanek G., Fingerle V., Hunfeld K.P. et al. Lyme borreliosis: clinical case definitions for diagnosis and management in Europe. Clin Microbiol Infect. 2011; 17(1): 69–79. doi: 10.1111/j.1469-0691.2010.03175.x.</mixed-citation><mixed-citation xml:lang="en">Stanek G., Fingerle V., Hunfeld K.P. et al. Lyme borreliosis: clinical case definitions for diagnosis and management in Europe. Clin Microbiol Infect. 2011; 17(1): 69–79. doi: 10.1111/j.1469-0691.2010.03175.x.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Bratton R.L., Whiteside J.W., Hovan M.J. et al. Diagnosis and treatment of Lyme disease. Mayo Clin Proc. 2008; 83(5): 566–71. doi: 10.4065/83.5.566.</mixed-citation><mixed-citation xml:lang="en">Bratton R.L., Whiteside J.W., Hovan M.J. et al. Diagnosis and treatment of Lyme disease. Mayo Clin Proc. 2008; 83(5): 566–71. doi: 10.4065/83.5.566.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
