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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">avk</journal-id><journal-title-group><journal-title xml:lang="ru">Архивъ внутренней медицины</journal-title><trans-title-group xml:lang="en"><trans-title>The Russian Archives of Internal Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2226-6704</issn><issn pub-type="epub">2411-6564</issn><publisher><publisher-name>“SINAPS” LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20514/2226-6704-2023-13-2-97-109</article-id><article-id custom-type="elpub" pub-id-type="custom">avk-1592</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEW ARTICLES</subject></subj-group></article-categories><title-group><article-title>Лечение пациентов с хронической ишемической болезнью сердца и сахарным диабетом 2 типа</article-title><trans-title-group xml:lang="en"><trans-title>Treatment of Patients Chronic Coronary Heart Disease and Type 2 Diabetes Mellitus</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9022-6155</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Щукина</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Shсhukina</surname><given-names>E. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Елена Викторовна Щукина</p><p>Донецк, ДНР</p></bio><bio xml:lang="en"><p>Elena V. Shсhukina</p><p>Donetsk, DPR</p></bio><email xlink:type="simple">schukina.elena@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2127-6925</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Приколота</surname><given-names>О. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Prikolota</surname><given-names>O. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Донецк, ДНР</p></bio><bio xml:lang="en"><p>Donetsk, DPR</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9720-0276</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Багрий</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Bagrij</surname><given-names>V. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Донецк, ДНР</p></bio><bio xml:lang="en"><p>Donetsk, DPR</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5436-7463</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Андрусяк</surname><given-names>А. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Andrusjak</surname><given-names>A. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Донецк, ДНР</p></bio><bio xml:lang="en"><p>Donetsk, DPR</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7536-981X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Рыбалко</surname><given-names>Г. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Rybalko</surname><given-names>G. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Донецк, ДНР</p></bio><bio xml:lang="en"><p>Donetsk, DPR</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8877-0066</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шестерина</surname><given-names>Ю. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Shesterina</surname><given-names>Yu. B.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Донецк, ДНР</p></bio><bio xml:lang="en"><p>Donetsk, DPR</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3513-3212</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Стефано</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Stefano</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Донецк, ДНР</p></bio><bio xml:lang="en"><p>Donetsk, DPR</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Государственная образовательная организация высшего профессионального образования «Донецкий национальный медицинский Университет им. М. Горького»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>State Educational Institution of Higher Professional Education «M. Gorky Donetsk National Medical University»</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>05</day><month>04</month><year>2023</year></pub-date><volume>13</volume><issue>2</issue><fpage>97</fpage><lpage>109</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Щукина Е.В., Приколота О.А., Багрий В.А., Андрусяк А.Ю., Рыбалко Г.С., Шестерина Ю.Б., Стефано Е.А., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Щукина Е.В., Приколота О.А., Багрий В.А., Андрусяк А.Ю., Рыбалко Г.С., Шестерина Ю.Б., Стефано Е.А.</copyright-holder><copyright-holder xml:lang="en">Shсhukina E.V., Prikolota O.A., Bagrij V.A., Andrusjak A.Y., Rybalko G.S., Shesterina Y.B., Stefano E.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.medarhive.ru/jour/article/view/1592">https://www.medarhive.ru/jour/article/view/1592</self-uri><abstract><p>Сочетание хронической ишемической болезни сердца и сахарного диабета 2 типа у пациента имеет высокую медицинскую значимость и привлекает к себе растущее внимание мирового врачебного сообщества. Серьезные изменения, произошедшие в лечебной тактике у пациентов, имеющих сочетание ишемической болезни сердца и сахарного диабета 2 типа, требуют пристального внимания. Современные подходы к терапии этой группы пациентов включают в себя направления, улучшающие сердечно-сосудистый прогноз (изменение образа жизни, прием антитромботических препаратов, антигипертензивной терапии, гиполипидемических средств — статинов и нестатиновых гиполипидемических препаратов (которые показаны пациентам, тяжело переносящим лечение статинами), сахароснижающих препаратов), а также внимательное ведение синдрома стабильной стенокардии (прием антиангинальных средств, оценка возможностей реваскуляризации). Новая линия сахароснижающих препаратов обладает высокими кардиопротекторными свойствами, снижает интенсивность поражения сосудистого русла (вазопротекция), оказывает ренопротекцию. Стратегия выбора сахароснижающих препаратов претерпела ряд изменений и в данный момент обозначается, как «дифференцированная», что подразумевает необходимость выбора препарата с наибольшими органопротективными свойствами. Достижение целевых уровней гликированного гемоглобина (HbA1C ) в границах 7,0-8,0 % ассоциировано с наименьшим уровнем смертности пациентов. Кроме того, пациентам с сахарным диабетом 2 типа, в особенности имеющим ишемическую болезнь сердца, рекомендовано свести к минимуму эпизоды развития гипогликемических состояний. Данное сообщение ставит перед собой задачу подробно обсудить основные подходы к ведению пациентов с ишемической болезнью сердца и сахарным диабетом 2 типа, а также подходы к улучшению сердечно-сосудистого прогноза.</p></abstract><trans-abstract xml:lang="en"><p>The combination of chronic coronary heart disease and type 2 diabetes mellitus in a patient has high medical importance, because relevance of the problem increases every year. Modern requirements for the provision of high-quality medical care to patients with combined pathology require attentive assessment: we can’t deny the pathophysiological relationship of both diseases. Serious changes that occurred in the treatment tactics in relation to such patients require close attention of the medical community. Modern approaches of the therapy of this group of patients include treatment directions that improve the cardiovascular prognosis (lifestyle changes, anti-platelet therapy, antihypertensive therapy, statins and nonstatin lipid-lowering agents, which are indicated for patients who are difficult to tolerate statin treatment, glucose-lowering drugs), as well as careful management of stable angina syndrome (using of antianginal drugs, assessing the possibilities of revascularization). The therapeutic tactics of the new revision offers promising perspective regimens for taking antiplatelet therapy, lipid-lowering drugs. The new line of glucose-lowering drugs has high cardioprotective properties, reduces the intensity of vascular lesions (vasoprotection), and has renoprotective properties. The strategy of choosing glucose-lowering drugs has also undergone some changes: at the moment it is designated as «differentiated», which implies choosing a drug with the highest organoprotective properties. Achievement of target HbA1C levels in the range of 7.0-8.0 % is associated with the lowest patient mortality rate. In addition, to patients with type 2 diabetes mellitus, especially group with coronary heart disease, advised to minimize episodes of hypoglycemic conditions. Aim of this statement is to discuss in detail progressive approaches in the treatment of patients with chronic coronary heart disease and type 2 diabetes mellitus.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>ишемическая болезнь сердца</kwd><kwd>сахарный диабет 2 типа</kwd><kwd>сердечно-сосудистые заболевания</kwd><kwd>сердечно-сосудистый прогноз</kwd></kwd-group><kwd-group xml:lang="en"><kwd>coronary heart disease</kwd><kwd>type 2 diabetes mellitus</kwd><kwd>cardiovascular diseases</kwd><kwd>cardiovascular prognosis</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Ferrannini G, De Bacquer D, De Backer G, et al. EUROASPIRE V collaborators. Screening for glucose perturbations and risk factor management in dysglycemic patients with coronary artery disease — a persistent challenge in need of substantial improvement: a report from ESC EORP EUROASPIRE V. 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