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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">avk</journal-id><journal-title-group><journal-title xml:lang="ru">Архивъ внутренней медицины</journal-title><trans-title-group xml:lang="en"><trans-title>The Russian Archives of Internal Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2226-6704</issn><issn pub-type="epub">2411-6564</issn><publisher><publisher-name>“SINAPS” LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20514/2226-6704-2013-0-1-14-18</article-id><article-id custom-type="elpub" pub-id-type="custom">avk-171</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЩЕЕ ДЕЛО</subject></subj-group></article-categories><title-group><article-title>ЭФФЕКТИВНОСТЬ КОМПЛЕКСНЫХ ПРОБИОТИКОВ ПРИ ЗАПОРАХ У БЕРЕМЕННЫХ ЖЕНЩИН</article-title><trans-title-group xml:lang="en"><trans-title>ЭФФЕКТИВНОСТЬ КОМПЛЕКСНЫХ ПРОБИОТИКОВ ПРИ ЗАПОРАХ У БЕРЕМЕННЫХ ЖЕНЩИН</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Вялов</surname><given-names>С. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Вялов</surname><given-names>С. С.</given-names></name></name-alternatives><bio xml:lang="ru"><p>кафедра общей врачебной практики, г. Москва</p></bio><bio xml:lang="en"><p>кафедра общей врачебной практики, г. Москва</p></bio><email xlink:type="simple">editor@medarhive.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бакулин</surname><given-names>И. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Бакулин</surname><given-names>И. Г.</given-names></name></name-alternatives><bio xml:lang="ru"><p>кафедра гастроэнтерологии</p></bio><bio xml:lang="en"><p>кафедра гастроэнтерологии</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Хурасева</surname><given-names>А. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Хурасева</surname><given-names>А. Б.</given-names></name></name-alternatives><bio xml:lang="ru"><p>кафедра акушерства и гинекологии</p></bio><bio xml:lang="en"><p>кафедра акушерства и гинекологии</p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Яковлев</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Яковлев</surname><given-names>А. А.</given-names></name></name-alternatives><bio xml:lang="ru"><p>факультет повышения квалификации специалистов</p></bio><bio xml:lang="en"><p>факультет повышения квалификации специалистов</p></bio><xref ref-type="aff" rid="aff-4"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГБОУ ВПО «Российский университет дружбы народов»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>ГБОУ ВПО «Российский университет дружбы народов»</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ГБУЗ «Центральный научно-исследовательский институт гастроэнтерологии»;&#13;
ФГБОУ ВПО «Московский государственный университет пищевых производств»; &#13;
Медицинский институт усовершенствования врачей</institution><country>Россия</country></aff><aff xml:lang="en"><institution>ГБУЗ «Центральный научно-исследовательский институт гастроэнтерологии»; &#13;
ФГБОУ ВПО «Московский государственный университет пищевых производств»;&#13;
Медицинский институт усовершенствования врачей</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ГОУ ВПО «Курский государственный медицинский университет»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>ГОУ ВПО «Курский государственный медицинский университет»</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>ГОУ ВПО «Ростовский государственный медицинский университет»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>ГОУ ВПО «Ростовский государственный медицинский университет»</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2013</year></pub-date><pub-date pub-type="epub"><day>28</day><month>02</month><year>2013</year></pub-date><volume>0</volume><issue>1</issue><fpage>14</fpage><lpage>18</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Вялов С.С., Бакулин И.Г., Хурасева А.Б., Яковлев А.А., 2013</copyright-statement><copyright-year>2013</copyright-year><copyright-holder xml:lang="ru">Вялов С.С., Бакулин И.Г., Хурасева А.Б., Яковлев А.А.</copyright-holder><copyright-holder xml:lang="en">Вялов С.С., Бакулин И.Г., Хурасева А.Б., Яковлев А.А.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.medarhive.ru/jour/article/view/171">https://www.medarhive.ru/jour/article/view/171</self-uri><abstract><p>Сегодня известно, что почти каждая третья беременная женщина страдает от запоров, которые, несомненно, снижают качество жизни. Генез запоров при беременности более или менее изучен. Однако поиск новых фармакоагентов для коррекции запоров ограничен понятными рамками — препарат должен быть безопасен для здоровья беременной женщины и плода. Существующие или предлагаемые методы коррекции зачастую имеют слабую доказательную базу либо не могут широко использоваться из-за нежелательных явлений у женщин (боли, диарейный синдром). Все вышесказанное требует поиска новых эффективных методов профилактики и коррекции запоров. В связи с тем, что запоры нередко возникают по причине нарушения нормального состава микрофлоры кишечника, в ближайшей перспективе видится более широкое применение пробиотиков для коррекции запоров у беременных. В статье приводится теоретическое обоснование применения пробиотиков у беременных женщин с запорами и доказательная база эффективного и безопасного применения некоторых пробиотических штаммов во время беременности.</p></abstract><trans-abstract xml:lang="en"><p>Today we know that almost one of three pregnant women suffer from constipation, which undoubtedly reduces quality of life. Genesis of constipation during pregnancy is more or less studied. However, searching for new agents to correct constipation is limited by clear framework — drugs must be safe for the health of the pregnant woman and fetus. Existing or proposed correction methods often have weak evidence base or can't be widely used due to adverse events in women (pain, diarrhea syndrome). All of this requires search for new effective methods of prevention and correction of constipation. Constipation often occur due to disruption of the intestinal microflora in the short term seems more widespread use of probiotics for the correction of constipation in pregnancy. The article provides a theoretical basis for the use of probiotics in pregnant women with constipation and evidence of effective and safe use of certain probiotic strains during pregnancy.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>пробиотики</kwd><kwd>запоры</kwd><kwd>беременность</kwd></kwd-group><kwd-group xml:lang="en"><kwd>probiotics</kwd><kwd>constipation</kwd><kwd>pregnancy</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">компания Takeda</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Бондаренко В.М., Грачева Н.М., Мацулевич Т.З. Дисбактериозы кишечника у взрослых. 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