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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">avk</journal-id><journal-title-group><journal-title xml:lang="ru">Архивъ внутренней медицины</journal-title><trans-title-group xml:lang="en"><trans-title>The Russian Archives of Internal Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2226-6704</issn><issn pub-type="epub">2411-6564</issn><publisher><publisher-name>“SINAPS” LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20514/2226-6704-2024-14-1-52-62</article-id><article-id custom-type="edn" pub-id-type="custom">NUYXHW</article-id><article-id custom-type="elpub" pub-id-type="custom">avk-1719</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLE</subject></subj-group></article-categories><title-group><article-title>Предиктивная диагностика факторов риска развития саркопении у пожилых пациентов с сахарным диабетом 2 типа</article-title><trans-title-group xml:lang="en"><trans-title>Predictive Diagnostics of Risk Factors for the Development of Sarcopenia in Early Patients with Type 2 Diabetes</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2667-4842</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Самойлова</surname><given-names>Ю. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Samoilova</surname><given-names>Yu. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p> </p><p>Самойлова Ю.Г., </p><p>Томск.</p></bio><bio xml:lang="en"><p>Y.G. Samoilova, </p><p>Tomsk.</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9966-6686</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Матвеева</surname><given-names>М. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Matveeva</surname><given-names>M. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Матвеева Мария Владимировна,</p><p>Томск.</p></bio><bio xml:lang="en"><p>M.V. Matveeva,</p><p>Tomsk.</p></bio><email xlink:type="simple">matveeva.mariia@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3596-6732</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Хорошунова</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Khoroshunova</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Хорошунова Е.А.,</p><p>Томск.</p></bio><bio xml:lang="en"><p>E.A. Khoroshunova,</p><p>Tomsk.</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6212-4568</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Подчиненова</surname><given-names>Д. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Podchinenova</surname><given-names>D. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Подчиненова Д.В.,</p><p>Томск.</p></bio><bio xml:lang="en"><p>D.V. Podchinenova, </p><p>Tomsk.</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0006-1151-261X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Якимова</surname><given-names>Я. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Yakimova</surname><given-names>Ya. L.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Якимова Я.Л.,</p><p>Томск.</p></bio><bio xml:lang="en"><p>Ya.L. Yakimova,</p><p>Tomsk.</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО «Сибирский государственный медицинский университет» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal State Budgetary Educational Institution of Higher Education «Siberian Stat e Medical University» of the Ministry of Health of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>13</day><month>02</month><year>2024</year></pub-date><volume>14</volume><issue>1</issue><fpage>52</fpage><lpage>62</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Самойлова Ю.Г., Матвеева М.В., Хорошунова Е.А., Подчиненова Д.В., Якимова Я.Л., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Самойлова Ю.Г., Матвеева М.В., Хорошунова Е.А., Подчиненова Д.В., Якимова Я.Л.</copyright-holder><copyright-holder xml:lang="en">Samoilova Y.G., Matveeva M.V., Khoroshunova E.A., Podchinenova D.V., Yakimova Y.L.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.medarhive.ru/jour/article/view/1719">https://www.medarhive.ru/jour/article/view/1719</self-uri><abstract><p>Обоснование. Своевременная диагностика саркопении у пациентов с нарушениями углеводного обмена позволит повысить качество и продолжительность жизни. Цель: проанализировать наличие основных факторов риска развития саркопении у пациентов с пресаркопенией и СД 2 типа. Материалы и методы. Участвовало 82 пациента с СД 2 типа, которые были разделены на 2 группы: с пресаркопенией и группу сравнения. Проведены: анкетирование с помощью опросников (краткая форма оценки здоровья (Health Status Survey (SF-36)), оценка саркопении и качества жизни (Sarcopenia and Quality of Life — SarQoL), сила, помощь при ходьбе, подъем со стула, подъем по лестнице и падения — Strength, Assistance with walking, Rise from a chair, Climb stairs and Falls — SARC-F), определения физической активности (International questionnaire on physical activity — IPAQ), оценка скорости ходьбы, динамометрия, биоимпедансометрия, анализ лабораторных показателей. Статистическая обработка проводилась с помощью программного обеспечения Statistica IBM (русская версия). Достоверными различия считались при р &lt;0,05. Результаты. Чаще пациентов с пресаркопенией беспокоят онемение нижних конечностей, головокружение, снижение памяти, лабильность артериального давления, одышка при физической нагрузке. В обеих группах регистрировалось ожирение I ст. В основной группе снижена скорость ходьбы — 1,63 м/сек, по сравнению с группой сравнения — 1,25. Показатели гликемии у лиц с пресаркопенией выше -7,6 ммоль/л, чем в группе сравнения — 7,2. Уровень физической активности в основной группе ниже и составил 40 мин/ в сутки, а также снижен общий показатель качества жизни до 34,99. Пациенты с пресаркопенией чаще принимают: бигуаниды — 46 %, иНГЛТ-2 — 27 %, препараты сульфанилмочевины — 26 %, 46 % получают инсулинотерапию (р&lt;0,05). В группе с пресаркопенией снижена жировая масса, площадь и процентное содержание висцерального жира по сравнению с группой сравнения. Индекс аппендикулярной мускулатуры в 1-ой группе составил 7,0 кг/м², во второй 7,5 кг/м². В 1-ой группе снижено содержание протеинов, минералов и общего количества воды. В лабораторных показателях в группе с пресаркопенией зарегистрированы дислипидемия, гипокальциемия, более высокие значения HbA1c, по сравнению с группой сравнения. Заключение. Для первичного скрининга саркопении у больных с СД 2 типа можно использовать динамометрию и биоимпедансометрию. Поддержание целевых параметров гликемии, коррекция дислипидемии, компенсация недостатка витамина Д и гипокальциемии способствует сохранению мышечной массы и силы.</p></abstract><trans-abstract xml:lang="en"><p>Objective. Materials and methods: 82 patients with type 2 diabetes mellitus participated, which were divided into 2 groups: probable sarcopenia and comparison groups. Conducted: questionnaire surveys (Health Status Survey (SF-36)), Sarcopenia quality and life assessment (SarQoL)), strength, assistance with walking, getting up from a chair, climbing stairs and falling — Strength, Assisted walking, getting up from a chair, Climbing stairs and Falls (SARC-F)), assessment of walking speed and physical activity, carpal dynamometry, bioimpedancemetry, analysis of laboratory parameters. Results: the difference between the conducted questionnaires is statistically insignificant. According to bioimpedansometry, obesity of the 1st degree was recorded in the lesions. In the group with presarcopenia, the main decrease in body composition parameters decreases. In addition, in the main group, the rate of intake is reduced, and decompensation of carbohydrate and lipid metabolism occurs. Differences were considered significant at p &lt; 0.05. Conclusion. Dynamometry and bioimpedance can be used for primary screening of sarcopenia in patients with type 2 diabetes. Maintaining the main indicators of glycemia, correction of dyslipidemia, compensation for obesity D and hypocalcemia of obesity in muscle mass and mass.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>пресаркопения</kwd><kwd>биоимпедансометрия</kwd><kwd>сахарный диабет 2 типа</kwd><kwd>кистевая динамометрия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>presarcopenia</kwd><kwd>bioimpedancemetry</kwd><kwd>type 2 diabetes mellitus</kwd><kwd>hand dynamometry</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Дедов И.И., Шестакова М.В., Майоров А.Ю. и др. «Алгоритмы специализированной медицинской помощи больным сахарным диабетом». Сахарный диабет. 2021; 24(1S):1-148. doi: 10.14341/DM12802.</mixed-citation><mixed-citation xml:lang="en">Dedov I.I., Shestakova M.V., Mayorov A.Yu. et el. Standards of specialized diabetes care. 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