avkАрхивъ внутренней медициныThe Russian Archives of Internal Medicine2226-67042411-6564“SINAPS” LLC10.20514/2226-6704-2024-14-3-165-172AWPZXZavk-1790Research ArticleОБЗОРНЫЕ СТАТЬИREVIEW ARTICLESТромбоз воротной вены при циррозе печени. Часть 1: эпидемиология, патогенез, клиника, диагностика, влияние на прогнозPortal Vein Thrombosis in Liver Cirrhosis. Part 1: Epidemiology, Pathogenesis, Clinic, Diag-nosis, Impact on Prognosishttps://orcid.org/0000-0002-5727-1640ЯгодаА. В.YagodaA. V.

Ставрополь

Stavropol

https://orcid.org/0000-0001-6392-8461КоройП. В.KoroyP. V.

Ставрополь

Stavropol

https://orcid.org/0009-0001-4146-3437БайсаеваЛ. С.BaisaevaL. S.

Ставрополь

Stavropol

https://orcid.org/0009-0006-7244-3507ДудовТ. Р.DudovT. R.

Темирлан Русланович Дудов

Ставрополь

Temirlan R. Dudov

Stavropol

timur222123@mail.ruФГБОУ ВО «Ставропольский государственный медицинский университет» Минздрава РоссииРоссияStavropol State Medical University,Russian FederationГБУЗ СК «Ставропольская краевая клиническая больница»РоссияStavropol Regional Clinical HospitalRussian Federation202411062024143165172Copyright © Ягода А.В., Корой П.В., Байсаева Л.С., Дудов Т.Р., 20242024Ягода А.В., Корой П.В., Байсаева Л.С., Дудов Т.Р.Yagoda A.V., Koroy P.V., Baisaeva L.S., Dudov T.R.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.medarhive.ru/jour/article/view/1790

   Тромбоз воротной вены является самым распространенным тромботическим осложнением у больных циррозом печени, особенно в случаях тяжелых форм. Патогенез носит мультифакторный характер, определяется изменением равновесия между системами свертывания и противосвертывания. Тромбоз часто протекает бессимптомно, обнаруживается случайно, хотя может осложняться варикозным кровотечением, ишемией кишечника, портальной билиопатией. Ультразвуковое допплеровское исследование является методом скрининга, в качестве альтернативы используются компьютерная томография, магнитно-резонансная томография. В обзоре освещены данные об эпидемиологии, факторах риска, клинических особенностях, диагностике тромбоза воротной вены у пациентов с циррозом печени. Приведены данные о влиянии тромбоза воротной вены на прогрессирование цирроза, выживаемость больных, в том числе после трансплантации печени.

   Portal vein thrombosis is the most common thrombotic complication in patients with liver cirrhosis, especially in cases of severe forms. The pathogenesis is multifactorial in nature, it determined by a change in the balance between the coagulation and anticoagulation systems. Thrombosis is often asymptomatic and is accidentally detected, although it can be complicated by varicose bleeding, intestinal ischemia, and portal biliopathy. Ultrasound Doppler examination is a screening method, as an alternative, computed tomography and magnetic resonance imaging are used. The review highlights data on epidemiology, risk factors, clinical features, and diagnosis of portal vein thrombosis in patients with liver cirrhosis. The data on the effect of portal vein thrombosis on the progression of liver cirrhosis and the survival of patients, including after liver transplantation, are presented.

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The authors declare that there are no conflicts of interest present.