avkАрхивъ внутренней медициныThe Russian Archives of Internal Medicine2226-67042411-6564“SINAPS” LLC10.20514/2226-6704-2013-0-3-57-62avk-195Research ArticleНЕРВНЫЕ БОЛЕЗНИДИАБЕТИЧЕСКАЯ АВТОНОМНАЯ КАРДИАЛЬНАЯ НЕЙРОПАТИЯ У БОЛЬНЫХ САХАРНЫМ ДИАБЕТОМ 2 ТИПА: ФОКУС НА НЕРЕШЁННЫЕ ПРОБЛЕМЫДИАБЕТИЧЕСКАЯ АВТОНОМНАЯ КАРД ИАЛЬНАЯ НЕЙРОПАТИЯ У БОЛЬНЫХ САХАРНЫМ ДИАБЕТОМ 2 ТИПА: ФОКУС НА НЕРЕШЁННЫЕ ПРОБЛЕМЫСтаценкоМ. Е.СтаценкоМ. Е.

кафедра внутренних болезней педиатрического и стоматологического факультетов

кафедра внутренних болезней педиатрического и стоматологического факультетов

mestatsenko@rambler.ruТуркинаС. В.ТуркинаС. В.

кафедра внутренних болезней педиатрического и стоматологического факультетов

кафедра внутренних болезней педиатрического и стоматологического факультетов

mestatsenko@rambler.ruГОУ ВПО «Волгоградский государственный медицинский университет»РоссияГОУ ВПО «Волгоградский государственный медицинский университет»Russian Federation201328062013035762Copyright © Стаценко М.Е., Туркина С.В., 20132013Стаценко М.Е., Туркина С.В.Стаценко М.Е., Туркина С.В.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.medarhive.ru/jour/article/view/195

Хорошо известно, что АКН является неблагоприятным прогностическим фактором при СД, увеличивающим показатель смертности пациентов. Возможно, АКН негативно влияет на течение СД даже в большей степени, чем часто обсуждаемые факторы риска сердечно-сосудистых событий. Это может быть связано с вегетативным дисбалансом регуляции кардиальных функций симпатического и парасимпатического отделов нервной системы. В настоящем обзоре представлены данные эпидемиологии, патофизиологии, клинической картины и диагностика АКН при СД 2 типа, приводятся современные подходы к профилактике и лечению АКН.

It is well known that cardiac autonomic neuropathy (CAN) is the negative prognostic factor which increases mortality in patients with diabetes mellitus. CAN may have greater predictive power for cardiovascular events than traditional risk factors. Significant morbidity and mortality can now be attributable to autonomic imbalance between the sympathetic and parasympathetic nervous system regulation of cardiovascular function. This review covers the epidemiology, pathophysiology, clinical presentation, and diagnosis of CAN in diabetes and discusses current evidence on approaches to prevention and treatment of CAN.

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The authors declare that there are no conflicts of interest present.