avkАрхивъ внутренней медициныThe Russian Archives of Internal Medicine2226-67042411-6564“SINAPS” LLC10.20514/2226-6704-2025-15-6-415-425VATKXMavk-2128Research ArticleОРИГИНАЛЬНЫЕ СТАТЬИORIGINAL ARTICLEФерменты печени при неалкогольной жировой болезни печени: ответ на пирамидальную аэробную тренировку в сравнении с непрерывной аэробной тренировкойLiver Enzymes in Non -Alcoholic Fatty Liver Di seases: Response to Pyram idal Versus Continuous Aerobic Traininghttps://orcid.org/0000-0003-1447-8817ИсмаилАли Мохамед АлиIsmailAli Mohamed Ali

Али Мохамед Али Исмаил — доцент, к.м.н. 

Гиза 

Ali Mohamed Ali Ismail — Assistant professor, PhD 

Giza 

ali.mohamed@pt.cu.edu.eghttps://orcid.org/0000-0001-6929-6565С.СалламСаллам АлиS. SallamSallam Ali

Саллам Али С. Саллам — преподаватель, физиотерапевт, к.м.н. 

Кена

Sallam Ali S. Sallam — Lecturer, PT, PhD 

Qena 

sallampt@svu.edu.egСалемИбрагим АбдельрафеяSalemIbrahim Abdelrafea

Ибрагим Абдельрафеа Салем — преподаватель, магистр наук 

Каир 

Ibrahim Abdelrafea Salem — Lecturer, Msc 

Cairo 

ibrahim.salem@pt.mti.edu.eghttps://orcid.org/0009-0008-6212-0370Аль-ЭмраниАсмаа М.Al-EmranyAsmaa M.

Асмаа М. Аль-Эмрани — лектор, к.м.н. 

город им. 6 Октября 

Asmaa M. Al-Emrany — Lecturer, P h.D 

6th of October 

amalemrany@msa.edu.eghttps://orcid.org/0009-0001-9345-7899ЭЛСагерМомен ЭЛСайедELsagherMomen ELsaied

Момен Эльсаид Эльсагер — доцент, к.м.н. 

Амман 

Momen ELsaied ELsagher — Assistant Professor, Ph.D 

Amman 

momen.elsaied@iu.edu.johttps://orcid.org/0009-0008-9578-3517АбдельазизАмира ХассанAbdelazizAmira Hassan

Амира Хассан Абдельазиз — преподаватель, к.м.н. 

Гиза 

Amira Hassan Abdelaziz — Lecturer, Ph.D 

Giza 

amira.hassan@acu.edu.eghttps://orcid.org/0009-0008-0764-2037МаруфАхмед Ясир МостафаMaroufAhmed Yasser Mostafa

Ахмед Яссер Мостафа Маруф — бакалавр физиотерапии 

Амман 

Ahmed Yasser Mostafa Marouf — Bachelor of Physical Therapy 

Amman 

ahmedelfahl2021@gmail.comhttps://orcid.org/0000-0003-4089-323XДразРами СаламаDrazRamy Salama

Рами Салама Драз — преподаватель, доктор философии 

Гиза;  Александрия 

Ramy Salama Draz — Lecturer, Ph.D 

Giza; Alexandria 

dr.ramy.salama@gmail.comКафедра физиотерапии при сердечно-сосудистых/респираторных заболеваниях и гериатрии, факультет физиотерапии, Каирский университетЕгипетDepartment of Physical Therapy for Cardiovascular/Respiratory Disorder and Geriatrics, Faculty of Physical Therapy, Cairo UniversityEgyptКафедра фундаментальных наук, факульт ет физиотерапии, Университет Южной Долины ; Директор программы физиотерапии, Университет Южной ДолиныЕгипетDepartment of Basic Science, Faculty of Physical Therapy, South Valley University ; Director of Physical Therapy Program, South Valley National universityEgyptКафедра физиотерапии в педиатрии и хирургии, факультет физиотерапии, Современный университет технологий и информацииЕгипетDepartment of Physical Therapy for Pediatrics and its Surgeries, Faculty of physical therapy, Modern University for Technology and InformationEgyptКафедра физиотерапии внутренних болезней и гериатрии, факультет физиотерапии, Октябрьский университет современных наук и искусствЕгипетDepartment of Physical Therapy for Internal Medicine and Geriatrics, Faculty of Physical Therapy, October University for Modern Sciences and ArtsEgyptКафедра физиотерапии, факультет смежных медицинских наук, Университет ИсраИорданияDepartment of Physical Therapy, Faculty of Allied Medical Sciences, Isra UniversityJordanКафедра физиотерапии для женского здоровья, факультет физиотерапии, Канадский университет Ахрама (ACU)ЕгипетDepartment of Physical Therapy For Women Health, Faculty of Physical Therapy, Ahram Canadian University (ACU)EgyptКафедра физиотерапии, факультет смежных медицинских наук, Филадельфийский университетИорданияBachelor of Physical Therapy, Department of Physical Therapy, Faculty of Allied Medical Sciences Philadelphia UniversityJordanКафедра физиотерапии при сердечно-сосудистых/респираторных заболеваниях и гериатрии, факультет физиотерапии, Каирский университет ; Кафедра сердечно-сосудистой, легочной и гериатрической медицины, факультет физиотерапии, Фаросский университетЕгипетDepartment of Physical Therapy for Cardiovascular/Respiratory Disorder and Geriatrics, Faculty of Physical Therapy, Cairo University ; Department of Cardiovascular Pulmonary and Geriatrics, Faculty of Physical Therapy, Pharos Un iversityEgypt202501122025156415425Copyright © Исмаил А., С.Саллам С., Салем И., Аль-Эмрани А., ЭЛСагер М., Абдельазиз А., Маруф А., Драз Р., 20252025Исмаил А., С.Саллам С., Салем И., Аль-Эмрани А., ЭЛСагер М., Абдельазиз А., Маруф А., Драз Р.Ismail A., S. Sallam S., Salem I., Al-Emrany A., ELsagher M., Abdelaziz A., Marouf A., Draz R.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.medarhive.ru/jour/article/view/2128

Цель. Исследовалось влияние выбора типа тренировки (консервативная нефармакологическая терапия первой линии при неалкогольной жировой болезни печени ( НАЖБП)) на улучшение показателей ферментов печени. Проведено сравнительное исследование, направленное на оценку ответа ферментов печени на пирамидальные упражнения с повышающейся интенсив ностью (интервальные) в сравнении с непрерывными аэробными упражнениями у пациенток женского пола с НАЖБП. Материалы и методы. 38 участниц с НАЖБП рандомизировал и в группу пирамидальных тренировок (n=19) и группу непрерывных тренировок средней интенсивности (n=19). Участницы обеих групп соблюдали рассчитанную на 12 недель диету с ни зким потреблением калорий и выполняли упражнения три раза в неделю. В дополнение к измерению индекса мас сы тела (ИМТ) и окружности талии (ОТ) у пациенток с НАЖБП определяли уровни сывороточной аланинтрансаминазы (АЛТ), щелочной фосфатазы (ЩФ), липопротеинов высокой плотности (ЛПВП), аспартатаминотрансферазы (АСТ), триглицеридов (ТГ) и гаммаглутаминтрансферазы (ГГТ) н а исходном уровне и через 12 недель. Результаты. По завершении обеих программ тренировок наблюдались заметные улучшения. Пирамидальные аэробные упражнения привели к более существенным и заметным улучшениям показателей по сравнению со вторым типом тренировок (аэробные тренировки умеренной интенсивности). Заключение. Оба типа тренировок (аэробные тренировки умеренной интенсивности или пирамидальные упражнения) существенно улучшили показатели АЛТ, ИМТ, АСТ, ЛПВП, ГГТ, ЩФ, ОТ и ТГ у пациенток с НАЖБП, при этом пирамидальные тренировки оказались более эффективными по сравнению с непрерывными упражнениями умеренной интенсивности.

Purpose: The effect of choosing the type of exercise — the first-line conservative non-pharmacological therapy in managing non-alcoholic fatty liver disease (NAFLD) — on improving liver enzymes has not been fully investigated.: This was a comparative trial aimed to examine the response of liver enzymes to pyramidal progressive-intensity (interval) versus continuous moderate-intensity aerobic training in NAFLD women. Materials and Methods: Thirty-eight NAFLD women were randomized into a pyramidal training group (n=19) and a group of continuous moderate-intensity exercise (n=19). Both groups followed a reviewed 12-week low-calorie diet and received exercise training thrice weekly. Besides body mass index (BMI) and abdominal circumference (AC), NAFLD patients’ serum alanine transaminase enzyme (ALTE), alkaline phosphatase enzyme (ALPE), high-density lipoprotein (HDL), aspartate transaminase enzyme (ASTE), triglycerides (TGs), and gamma-glutamyl-transpeptidase enzyme (GGTE) were assessed before and after 12 weeks. Results: Significant improvements in all outcomes occurred after finishing both training forms. The pyramidal aerobic form produced more significant and pronounced improvements in the tested outcomes compared to the other form of exercise, moderate-intensity aerobic exercise. Conclusion: Both training forms, moderate-intensity aerobic exercise or pyramidal training, significantly improved NAFLD patients’ ALTE, BMI, ASTE, HDL, GGTE, AC, ALPE, and TGs, but the pyramidal form of exercise is more efficient than the continuous moderate-intensity form.

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The authors declare that there are no conflicts of interest present.