avkАрхивъ внутренней медициныThe Russian Archives of Internal Medicine2226-67042411-6564“SINAPS” LLC10.20514/2226-6704-2026-16-2-96-103KGZJWDavk-2213Research ArticleОБЗОРНЫЕ СТАТЬИREVIEW ARTICLESМикрососудистая стенокардия: патофизиология снижения коронарного резерваMicrovascular Angina Pectoris: The Pathophysiology of Decreased Coronary ReserveКравченкоМ. А.KravchenkoM. A.

Кравченко Марина Александровна — студентка 5 курса  

Новосибирск 

Marina A. Kravchenko — 5th-year student 

Novosibirsk 

m.kravchenko02@mail.ruhttps://orcid.org/0000-0002-1250-8798ХидироваЛ. Д.KhidirovaL. D.

Хидирова Людмила Даудовна — доктор медицинских наук, профессор кафедры; ведущий кардиолог 

Новосибирск 

Lyudmila D. Khidirova — Doctor of Medical Sciences, Professor; Leading Cardiologist

Novosibirsk 

h_ludmila73@mail.ruНовосибирский клинический кардиологический диспансерРоссияNovosibirsk Clinical Cardiology DispensaryRussian FederationФГБОУ ВО Новосибирский государственный медицинский университет Минздрава России, кафедра фармакологии, клинической фармакологии и доказательной медицины ; Новосибирский клинический кардиологический диспансерРоссияNovosibirsk State Medical University of the Ministry of Health of the Russian Federation, Department of Pharmacology, Clinical Pharmacology and Evidence-Based Medicine ; Novosibirsk Clinical Cardiology DispensaryRussian Federation20262803202616296103Copyright © Кравченко М.А., Хидирова Л.Д., 20262026Кравченко М.А., Хидирова Л.Д.Kravchenko M.A., Khidirova L.D.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.medarhive.ru/jour/article/view/2213

Проведен обзор современной российской и зарубежной литературы, посвященной проблеме нарушенного коронарного резерва кровотока как проявление микрососудистой дисфункции. При поиске информации по этому вопросу использованы материалы следующих баз данных: РИНЦ, Best Evidence, Scopus, Elsevier, PubMed, Clinical Evidence, Cochrane Library. Нарушение коронарного резерва кровотока — важное проявление микрососудистой дисфункции и ключевой диагностический критерий микроваскулярной стенокардии. Оценка этого показателя имеет высокую прогностическую и терапевтическую значимость. Учитывая гетерогенность патогенеза, дальнейшие исследования необходимы для персонализированного подхода к лечению пациентов с микроваскулярной стенокардией.

A review of modern Russian and foreign literature on the problem of impaired coronary blood flow reserve as a manifestation of microvascular dysfunction has been conducted. When searching for information on this issue, materials from the following databases were used: RSCI, Best Evidence, Scopus, Elsevier, PubMed, Clinical Evidence, Cochrane Library. Violation of the coronary blood flow reserve is an important manifestation of microvascular dysfunction and a key diagnostic criterion for microvascular angina. The evaluation of this indicator has high prognostic and therapeutic significance. Given the heterogeneity of pathogenesis, further research is needed for a personalized approach to the treatment of patients with microvascular angina.

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The authors declare that there are no conflicts of interest present.