avkАрхивъ внутренней медициныThe Russian Archives of Internal Medicine2226-67042411-6564“SINAPS” LLC10.20514/2226-6704-2014-0-3-67-72avk-307Research ArticleОБЩЕЕ ДЕЛОСТРУКТУРНО-ФУНКЦИОНАЛЬНЫЕ ИЗМЕНЕНИЯ МИОКАРДА ПРИ ОЖИРЕНИИ, ИХ ДИНАМИКА НА ФОНЕ СНИЖЕНИЯ МАССЫ ТЕЛА (литературный обзор)СТРУКТУРНО-ФУНКЦИОНАЛЬНЫЕ ИЗМЕНЕНИЯ МИОКАРДА ПРИ ОЖИРЕНИИ, ИХ ДИНАМИКА НА ФОНЕ СНИЖЕНИЯ МАССЫ ТЕЛА (литературный обзор)ПостоеваА. В.ПостоеваА. В.

кафедра терапии, эндокринологии и скорой медицинской помощи, г. Архангельск

кафедра терапии, эндокринологии и скорой медицинской помощи, г. Архангельск

ann-primak@yandex.ruДворяшинаИ. В.ДворяшинаИ. В.

кафедра терапии, эндокринологии и скорой медицинской помощи, г. Архангельск

кафедра терапии, эндокринологии и скорой медицинской помощи, г. Архангельск

ann-primak@yandex.ruГБОУ ВПО «Северный государственный медицинский университет»РоссияГБОУ ВПО «Северный государственный медицинский университет»Russian Federation201428062014036772Copyright © Постоева А.В., Дворяшина И.В., 20142014Постоева А.В., Дворяшина И.В.Постоева А.В., Дворяшина И.В.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.medarhive.ru/jour/article/view/307

Целью данной работы явилось обобщение имеющихся литературных данных о структурно-функциональных изменениях миокарда у больных ожирением разной выраженности, описание возможных патогенетических механизмов данных изменений и их динамики на фоне снижения МТ. У пациентов с ожирением наряду с сохраняющейся нормальной геометрией ЛЖ ряд авторов определял преобладание эксцентрической ГЛЖ, в то время как другие авторы чаще описывали концентрическую гипертрофию. Большинством авторов выявлены сохранная систолической функция и субклиническая диастолическая дисфункция. При лечении ожирения отмечается уменьшение абсолютной и индексированной ММЛЖ, получены положительные корреляции с динамикой антропометрических показателей.

The aim of the study was the literature review of data about structural and functional changes of the myocardium in patients with different degrees of obesity, possible pathogenetic mechanisms of these changes and their dynamics in weight reduction. Some authors found normal geometry of left ventricular in people with obesity, whereas others got eccentric or concentric hypertrophy in the most of patients. The majority of the authors diagnosed normal systolic function and subclinical diastolic function. Absolute and indexed myocardium mass of left ventricular decreased after weight loss, positive correlations between their dynamics and anthropometric parameters were observed.

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The authors declare that there are no conflicts of interest present.