avkАрхивъ внутренней медициныThe Russian Archives of Internal Medicine2226-67042411-6564“SINAPS” LLC10.20514/2226-6704-2014-0-6-58-65avk-422Research ArticleОБЩЕЕ ДЕЛОЛИХОРАДКА НЕЯСНОГО ГЕНЕЗА: «ПО НАПРАВЛЕНИЮ К СТИЛЛУ»ЛИХОРАДКА НЕЯСНОГО ГЕНЕЗА: «ПО НАПРАВЛЕНИЮ К СТИЛЛУ»ДворецкийЛ. И.ДворецкийЛ. И.dvoretski@mail.ruГОУ ВПО «Первый Московский государственный медицинский университет им. И.М. Сеченова», кафедра госпитальной терапии No 2, г. МоскваRussian Federation201428122014065865Copyright © Дворецкий Л.И., 20142014Дворецкий Л.И.Дворецкий Л.И.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.medarhive.ru/jour/article/view/422

В статье приводятся основные критерии клинической ситуации, обозначающейся как «лихорадка неясного генеза» и представляющей собой междисциплинарную клиническую проблему. Основными причинами ЛНГ являются инфекционно-воспалительные процессы, злокачественные опухоли, неинфекционные воспалительные (ревматические, системные) и прочие заболевания. В группе неинфекционных воспалительных заболеваний среди больных ЛНГ важное место занимает БСВ. Обсуждаются исторические аспекты описания заболевания, диагностические критерии, вопросы дифференциальной диагностики болезни Стилла и её место у больных ЛНГ. Приводится описание двух пациентов с ЛНГ, у которых была диагностирована болезнь Стилла, характеризующаяся рядом особенностей. 

The article provides the basic criteria of the clinical situation known as «fever of unknown origin» which is an interdisciplinary clinical problem. The main reasons for fever of unknown origin are infectious-inflammatory processes, malignant tumors, non-infectious inflammatory (rheumatic fever, systemic disease) and other diseases. In the group of non-infectious inflammatory diseases among patients with fever of unknown origin Still’s disease in adults occupies an important place. The author discusses the historical aspects of the description of the disease, diagnostic criteria, differential diagnosis of Still’s disease and its place in patients with fever of unknown origin; describes two patients with fever of unknown origin, diagnosed with Still’s disease by a number of features. 

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The authors declare that there are no conflicts of interest present.