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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">avk</journal-id><journal-title-group><journal-title xml:lang="ru">Архивъ внутренней медицины</journal-title><trans-title-group xml:lang="en"><trans-title>The Russian Archives of Internal Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2226-6704</issn><issn pub-type="epub">2411-6564</issn><publisher><publisher-name>“SINAPS” LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20514/2226-6704-2015-0-5-18</article-id><article-id custom-type="elpub" pub-id-type="custom">avk-457</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLE</subject></subj-group></article-categories><title-group><article-title>ПСИХОСОМАТИЧЕСКИЕ АСПЕКТЫ ЛЕЧЕНИЯ ГАСТРОЭЗОФАГЕАЛЬНОЙ РЕФЛЮКСНОЙ БОЛЕЗНИ</article-title><trans-title-group xml:lang="en"><trans-title>PSYCHOSOMATIC ASPECTS IN THE TREATMENT OF GASTROESOPHAGEAL REFLUX DISEASE</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Трофимов</surname><given-names>В. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Trofimov</surname><given-names>V. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>кафедра госпитальной терапии,</p><p>г. Санкт-Петербург</p></bio><bio xml:lang="en"><p>Department of hospital therapy,</p><p>Saint Petersburg</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Безруков</surname><given-names>Ю. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Bezrukov</surname><given-names>Yu. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>кафедра госпитальной терапии,</p><p>г. Санкт-Петербург</p></bio><bio xml:lang="en"><p>Department of hospital therapy,</p><p>Saint Petersburg</p></bio><email xlink:type="simple">yur-bezrukov@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГБОУ ВПО «Первый Санкт-Петербургский государственный медицинский университет имени академика И.П. Павлова»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Pavlov First Saint Petersburg State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2015</year></pub-date><pub-date pub-type="epub"><day>28</day><month>10</month><year>2015</year></pub-date><volume>0</volume><issue>5</issue><fpage>55</fpage><lpage>61</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Трофимов В.И., Безруков Ю.Н., 2015</copyright-statement><copyright-year>2015</copyright-year><copyright-holder xml:lang="ru">Трофимов В.И., Безруков Ю.Н.</copyright-holder><copyright-holder xml:lang="en">Trofimov V.I., Bezrukov Y.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.medarhive.ru/jour/article/view/457">https://www.medarhive.ru/jour/article/view/457</self-uri><abstract><p>Гастроэзофагеальная рефлюксная болезнь является наиболее распространённым заболеванием пищевода, в основе развития которой лежит нарушение двигательной функции верхних отделов пищеварительной системы, что позволяет это заболевание вполне отнести к категории психосоматических, особенно на ранних этапах развития, когда не проявились органические осложнения, затрагивающие структуру тканей. Значительный процент психических нарушений отмечается у пациентов еще до развития соматических жалоб. Обследованы пациенты в количестве 105 человек. Первая группа — опытная (71 больной) получала комплексное лечение, включающее базисное патогенетическое, симптоматическое, а так же психотропное лечение в виде анксиолитиков и антидепрессантов. Выбор препарата осуществлялся по результатам психологического тестирования. Вторая группа — группа сравнения (34 пациента) получала только традиционное лечение, без психотропной поддержки. Был проведен анализ астено-вегетативного синдрома, психологических особенностей пациентов в плане отношения к своему заболеванию, показателей тревожности и уровня выраженности депрессии. У больных с неэрозивной рефлюксной болезнью частота выявления депрессии и тревожности была более чем в 2 раза выше, чем у больных с эрозивной рефлюксной болезнью. После проведения психотропного лечения данные показатели практически сравнялись. Назначение психотропной терапии в виде антидепрессантов и анксиолитиков позволило обеспечить минимизацию сроков регрессии клинических и психосоматических проявлений заболевания.</p></abstract><trans-abstract xml:lang="en"><p>Gastroesophageal reflux disease is the most common disease of the esophagus, through the development of which is impaired motor function of the upper gastrointestinal system, allowing the disease to be quite be classified as psychosomatic, especially in the early stages of development, when no apparent organic complications that affect the structure of tissues. A significant percentage of mental disorders is observed in patients even before the development of somatic complaints. Patients in number of 105 people are examined. The first group — experienced (71 patient) received complex treatment, which includes the basic pathogenetic, symptomatic, and psychotropic treatment in the form of anxiolytics and antidepressants. The choice of drug was based on the results of psychological testing. The second group — the comparison group (34 patients) received only conventional treatment, without psychiatric support. Analysis was conducted of the astheno-vegetative syndrome, psychological characteristics of patients in relation to their disease, indicators of anxiety level and severity of depression. Patients with not erosive reflux disease have a frequency of detection of a depression and uneasiness was more than twice higher, than at patients with erosive reflux disease. After carrying out psychotropic treatment these indicators were practically made even. Prescription of psychotropic therapy in the form of antidepressants and anxiolytics has allowed to minimize the timing regression of clinical and psychosomatic manifestations of disease.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>психосоматические заболевания</kwd><kwd>депрессия</kwd><kwd>тревожность</kwd><kwd>гастроэзофагеальная рефлюксная болезнь</kwd><kwd>анксиолитики</kwd><kwd>антидепресанты</kwd></kwd-group><kwd-group xml:lang="en"><kwd>psychosomatic illnesses</kwd><kwd>depression</kwd><kwd>anxiety</kwd><kwd>gastroesophageal reflux disease</kwd><kwd>anxiolytics</kwd><kwd>antidepressants</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Гиндикин В.Я. Справочник: Соматогенные и соматоформные психические расстройства (клиника, дифференциальная диагностика, лечение). Москва. Триада-Х, 2002. 256 с.</mixed-citation><mixed-citation xml:lang="en">Gindikin V. I. 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