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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">avk</journal-id><journal-title-group><journal-title xml:lang="ru">Архивъ внутренней медицины</journal-title><trans-title-group xml:lang="en"><trans-title>The Russian Archives of Internal Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2226-6704</issn><issn pub-type="epub">2411-6564</issn><publisher><publisher-name>“SINAPS” LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20514/2226-6704-2016-6-3-19-24</article-id><article-id custom-type="elpub" pub-id-type="custom">avk-528</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEW ARTICLES</subject></subj-group></article-categories><title-group><article-title>НОВЫЕ ВОЗМОЖНОСТИ В ТЕРАПИИ СЕРДЕЧНО-СОСУДИСТОЙ ПАТОЛОГИИ С ИСПОЛЬЗОВАНИЕМ КОЛХИЦИНА</article-title><trans-title-group xml:lang="en"><trans-title>NEW POSSIBILITIES IN THE TREATMENT OF CARDIOVASCULAR DISEASE USING COLCHICINE</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ватутин</surname><given-names>Н. Т.</given-names></name><name name-style="western" xml:lang="en"><surname>Vatutin</surname><given-names>M. T.</given-names></name></name-alternatives><bio xml:lang="ru"><p>кафедра госпитальной терапии,</p><p>г. Донецк</p></bio><bio xml:lang="en"><p>department of hospital therapy,</p><p>Donetsk</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Смирнова</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Smyrnova</surname><given-names>G. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>кафедра госпитальной терапии,</p><p>г. Донецк</p></bio><bio xml:lang="en"><p>department of hospital therapy,</p><p>Donetsk</p></bio><email xlink:type="simple">a.smyrnova@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Целикова</surname><given-names>Е. О.</given-names></name><name name-style="western" xml:lang="en"><surname>Tselikova</surname><given-names>E. O.</given-names></name></name-alternatives><bio xml:lang="ru"><p>кафедра госпитальной терапии,</p><p>г. Донецк</p></bio><bio xml:lang="en"><p>department of hospital therapy,</p><p>Donetsk</p></bio><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Донецкий национальный медицинский университет им. М. Горького;&#13;
Институт неотложной и восстановительной хирургии им. В.К. Гусака</institution><country>Украина</country></aff><aff xml:lang="en"><institution>M. Gorky Donetsk National Medical University;&#13;
V.K. Gusak Institute of Urgent and Recovery Surgery</institution><country>Ukraine</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Донецкий национальный медицинский университет им. М. Горького</institution><country>Украина</country></aff><aff xml:lang="en"><institution>M. Gorky Donetsk National Medical University</institution><country>Ukraine</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2016</year></pub-date><pub-date pub-type="epub"><day>10</day><month>06</month><year>2016</year></pub-date><volume>6</volume><issue>3</issue><fpage>19</fpage><lpage>24</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Ватутин Н.Т., Смирнова А.С., Целикова Е.О., 2016</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="ru">Ватутин Н.Т., Смирнова А.С., Целикова Е.О.</copyright-holder><copyright-holder xml:lang="en">Vatutin M.T., Smyrnova G.S., Tselikova E.O.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.medarhive.ru/jour/article/view/528">https://www.medarhive.ru/jour/article/view/528</self-uri><abstract><p>В представленном обзоре литературы отражены вопросы фармакологических свойств и механизма действия колхицина. Авторами предоставлены результаты ряда научных работ, посвященных изучению эффекта колхицина на течение сердечно-сосудистых заболеваний.</p></abstract><trans-abstract xml:lang="en"><p>The present review of the literature reflects issues of the colchicine’s pharmacological properties and mechanism of action. The authors provided the results of a number of scientific studies dedicated to the effects of colchicine on the cardiovascular pathology.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>колхицин</kwd><kwd>сердечно-сосудистые заболевания</kwd></kwd-group><kwd-group xml:lang="en"><kwd>colchicine</kwd><kwd>cardiovascular disease</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Nidorf SM, Eikelboom JW, Budgeon CA, Thompson PL. Low-dose colchicine for secondary prevention of cardiovascular disease. 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