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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">avk</journal-id><journal-title-group><journal-title xml:lang="ru">Архивъ внутренней медицины</journal-title><trans-title-group xml:lang="en"><trans-title>The Russian Archives of Internal Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2226-6704</issn><issn pub-type="epub">2411-6564</issn><publisher><publisher-name>“SINAPS” LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20514/2226-6704-2017-7-3-171-180</article-id><article-id custom-type="elpub" pub-id-type="custom">avk-651</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEW ARTICLES</subject></subj-group></article-categories><title-group><article-title>ОСТРАЯ ПЕЧЕНОЧНАЯ НЕДОСТАТОЧНОСТЬ У ВЗРОСЛЫХ: ЭТИОЛОГИЯ, КЛИНИЧЕСКИЕ ПРОЯВЛЕНИЯ, МЕТОДЫ КОРРЕКЦИИ</article-title><trans-title-group xml:lang="en"><trans-title>ACUTE LIVER FAILURE IN ADULTS: ETIOLOGY, CLINICAL MANIFESTATIONS, METHODS OF CORRECTION</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лукашик</surname><given-names>С. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Lukashyk</surname><given-names>S. P.</given-names></name></name-alternatives><email xlink:type="simple">svetlanalukashik@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Карпов</surname><given-names>И. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Karpov</surname><given-names>I. A.</given-names></name></name-alternatives><email xlink:type="simple">svetlanalukashik@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>УО «Белорусский государственный медицинский университет», кафедра инфекционных болезней, Минск</institution><country>Беларусь</country></aff><aff xml:lang="en"><institution>Belarussian stat medical university, Department of Infectious Diseases, Minsk</institution><country>Belarus</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2017</year></pub-date><pub-date pub-type="epub"><day>28</day><month>05</month><year>2017</year></pub-date><volume>7</volume><issue>3</issue><fpage>171</fpage><lpage>180</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Лукашик С.П., Карпов И.А., 2017</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="ru">Лукашик С.П., Карпов И.А.</copyright-holder><copyright-holder xml:lang="en">Lukashyk S.P., Karpov I.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.medarhive.ru/jour/article/view/651">https://www.medarhive.ru/jour/article/view/651</self-uri><abstract><p>В статье проведена систематизация информации об этиологии, эпидемиологии и клинических проявлениях острой печеночной недостаточности. Приведены статистические данные о частоте ее встречаемости при разных нозологических формах, описаны наиболее часто развивающиеся осложнения, изложены основные подходы к терапии. Цель обзора — улучшить осведомленность врачей об острой печеночной недостаточности.</p><p> </p></abstract><trans-abstract xml:lang="en"><p>Information on etiology, epidemiology and clinical manifestations of acute liver failure is systemized. The review provides statistics on the frequency of its occurrence in different nosological manifestations, describes the most frequent developed complications and the main approaches to therapy. Aim: to raise awareness of acute liver failure among physicians.</p><p> </p></trans-abstract><kwd-group xml:lang="ru"><kwd>острая печеночная недостаточность</kwd><kwd>поражение печени</kwd><kwd>осложнения</kwd><kwd>методы терапии</kwd></kwd-group><kwd-group xml:lang="en"><kwd>acute liver failure</kwd><kwd>liver disease</kwd><kwd>complications</kwd><kwd>treatment</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Acharya S.K., Bhatia V., Sreenivas V. et al. Efficacy of L-ornithine L-aspartate in acute liver failure: a double-blind, randomized, placebo-controlled study. Gastroenterology. 2009; 136: 2159-2168.</mixed-citation><mixed-citation xml:lang="en">Acharya S.K., Bhatia V., Sreenivas V. et al. Efficacy of L-ornithine L-aspartate in acute liver failure: a double-blind, randomized, placebo-controlled study. 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