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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">avk</journal-id><journal-title-group><journal-title xml:lang="ru">Архивъ внутренней медицины</journal-title><trans-title-group xml:lang="en"><trans-title>The Russian Archives of Internal Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2226-6704</issn><issn pub-type="epub">2411-6564</issn><publisher><publisher-name>“SINAPS” LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20514/2226-6704-2017-7-6-462-468</article-id><article-id custom-type="elpub" pub-id-type="custom">avk-722</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>РАЗБОР КЛИНИЧЕСКИХ СЛУЧАЕВ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ANALYSIS OF CLINICAL CASES</subject></subj-group></article-categories><title-group><article-title>СЛОЖНЫЕ НАРУШЕНИЯ РИТМА И ПРОВОДИМОСТИ СЕРДЦА У ПАЦИЕНТКИ С ГИПОТИРЕОЗОМ (КЛИНИЧЕСКОЕ НАБЛЮДЕНИЕ)</article-title><trans-title-group xml:lang="en"><trans-title>COMPLEX DISORDERS OF HEART RHYTHM AND CONDUCTIVITY IN A PATIENT WITH HYPOTHYROIDISM (CLINICAL OBSERVATION)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Козлова</surname><given-names>Л. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Kozlova</surname><given-names>L. K.</given-names></name></name-alternatives><bio xml:lang="ru"><p> кафедра факультетской терапии и эндокринологии.</p><p>Оренбург.</p></bio><bio xml:lang="en"><p>Department of Faculty Therapy and Endocrinology.</p><p>Orenburg.</p></bio><email xlink:type="simple">lilikon@list.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кучма</surname><given-names>Г. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Kuchma</surname><given-names>G. B.</given-names></name></name-alternatives><bio xml:lang="ru"><p> кафедра факультетской терапии и эндокринологии.</p><p>Оренбург.</p></bio><bio xml:lang="en"><p>Department of Faculty Therapy and Endocrinology.</p><p>Orenburg.</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Турмухамбетова</surname><given-names>Б. Т.</given-names></name><name name-style="western" xml:lang="en"><surname>Turmukhambetova</surname><given-names>B. T.</given-names></name></name-alternatives><bio xml:lang="ru"><p> кафедра факультетской терапии и эндокринологии.</p><p>Оренбург.</p></bio><bio xml:lang="en"><p>Department of Faculty Therapy and Endocrinology.</p><p>Orenburg.</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ибрагимова</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Ibragimova</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Оренбург.</p></bio><bio xml:lang="en"><p>Orenburg.</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Соколова</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Sokolovа</surname><given-names>N. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Оренбург.</p></bio><bio xml:lang="en"><p>Orenburg.</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шатилов</surname><given-names>А. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Shatilov</surname><given-names>A. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Оренбург.</p></bio><bio xml:lang="en"><p>Orenburg.</p></bio><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Федеральное государственное бюджетное образовательное учреждение высшего образования «Оренбургский государственный медицинский университет» Министерства здравоохранения Российской Федерации (ФГБОУ ВО ОрГМУ Минздрава России).</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal State Budget Educational Institution of Higher Education «Orenburg State Medical University» of the Ministry of Health of the Russian Federation (FSBEI HE OrSMU of the Ministry of Health of Russia).</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Государственное бюджетное учреждение здравоохранения «Оренбургская областная клиническая больница» (ГБУЗ «ООКБ»).</institution><country>Россия</country></aff><aff xml:lang="en"><institution>The state budget health care institution «Orenburg Regional Clinical Hospital» (SBHI «ORCH»).</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2017</year></pub-date><pub-date pub-type="epub"><day>10</day><month>12</month><year>2017</year></pub-date><volume>7</volume><issue>6</issue><fpage>462</fpage><lpage>468</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Козлова Л.К., Кучма Г.Б., Турмухамбетова Б.Т., Ибрагимова Е.А., Соколова Н.В., Шатилов А.П., 2017</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="ru">Козлова Л.К., Кучма Г.Б., Турмухамбетова Б.Т., Ибрагимова Е.А., Соколова Н.В., Шатилов А.П.</copyright-holder><copyright-holder xml:lang="en">Kozlova L.K., Kuchma G.B., Turmukhambetova B.T., Ibragimova E.A., Sokolovа N.V., Shatilov A.P.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.medarhive.ru/jour/article/view/722">https://www.medarhive.ru/jour/article/view/722</self-uri><abstract><p>В статье описан клинический случай возникновения сложных нарушений ритма и проводимости сердца у пациентки 45 лет с декомпенсированным гипотиреозом. Приведены данные литературы о специфической кардиомиопатии, возникающей у пациентов с гипотиреозом, именуемой «гипотиреоидным сердцем», метаболических, гемодинамических изменениях на фоне гипотиреоза и возможных нарушениях ритма и проводимости сердца. В описанном клиническом примере дана история болезни пациентки, которая в течение последних 3 лет наблюдалась у эндокринолога по поводу гипотиреоза. На протяжении 6 месяцев, предшествующих данной госпитализации, прекратила приём левотироксина по собственной инициативе. Ухудшение отмечает в последние 3 месяца: появилась и стала нарастать клиника гипотиреоза, возникла частая экстрасистолия. При объективном осмотре — симптоматика выраженного гипотиреоза. Проведено всестороннее обследование пациентки, которое выявило атриовентрикулярную блокаду I степени, частую желудочковую экстрасистолию, удлинение интервала QT на ЭКГ, поздние потенциалы желудочков на фоне низкой концентрации натрия и калия в крови. В течение первых суток госпитализации произошла клиническая смерть. Прослежена чёткая положительная динамика на фоне терапии, направленной на коррекцию электролитных нарушений, а также заместительной гормональной терапии левотироксином.</p></abstract><trans-abstract xml:lang="en"><p>The article describes a clinical case of the occurrence of complex disorders of the heart rhythm and conductivity in a patient of 45 years with decompensated hypothyroidism. The literature data on specific cardiomyopathy appearing in patients with hypothyroidism (“hypothyroid heart”), metabolic, hemodynamic changes against the background of hypothyroidism and possible violations of heart rhythm and conductivity are given. In the described clinical case the patient’s medical history is given, who has been observed in an endocrinologist for hypothyroidism for the last 3 years. 6 months before this hospitalization patient stopped taking levothyroxine on her own initiative. She noticed deterioration in the last 3 months: the clinic of hypothyroidism appeared and began to grow, a frequent extrasystole appeared. At an objective survey — a symptomatology of the expressed hypothyroidism. A comprehensive examination of the patient was performed, which revealed atrioventricular blockade of the 1st degree, frequent ventricular extrasystole, prolongation of the QT interval on the ECG, late ventricular potentials against the background of low concentrations of sodium and potassium in the blood. During the first 24 hours of hospitalization, there was a clinical death. A clear positive dynamics was traced against the background of therapy aimed at the correction of electrolyte disorders, as well as hormone replacement therapy with levothyroxine.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>аутоиммунный тиреоидит</kwd><kwd>гипотиреоз</kwd><kwd>гипотиреоидное сердце</kwd><kwd>нарушения ритма сердца</kwd></kwd-group><kwd-group xml:lang="en"><kwd>autoimmune thyroiditis</kwd><kwd>hypothyroidism</kwd><kwd>hypothyroid heart</kwd><kwd>сardiac arrhythmias</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Батчаев Э.О. Особенности поражения сердца при первичном гипотиреозе: Дисс. …канд. мед. наук. — Санкт-Петербург, 2003. Batchaev E.O. Features of heart disease in primary hypothyroidism: Diss…. Cand. of med. sciences. — Saint-Petersburg. 2003</mixed-citation><mixed-citation xml:lang="en">Батчаев Э.О. 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