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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">avk</journal-id><journal-title-group><journal-title xml:lang="ru">Архивъ внутренней медицины</journal-title><trans-title-group xml:lang="en"><trans-title>The Russian Archives of Internal Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2226-6704</issn><issn pub-type="epub">2411-6564</issn><publisher><publisher-name>“SINAPS” LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20514/2226-6704-2018-8-4-247-259</article-id><article-id custom-type="elpub" pub-id-type="custom">avk-803</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ЛЕКЦИИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>LECTURES</subject></subj-group></article-categories><title-group><article-title>АЛГОРИТМ ВЕДЕНИЯ ПАЦИЕНТОВ С ОСТРОЙ СЕРДЕЧНОЙ НЕДОСТАТОЧНОСТЬЮ</article-title><trans-title-group xml:lang="en"><trans-title>ALGORITHM FOR THE TREATMENT OF PATIENTS WITH ACUTE HEART FAILURE</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Резник</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Reznik</surname><given-names>E. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кафедра госпитальной терапии № 2 лечебного факультета,</p><p>Москва</p></bio><bio xml:lang="en"><p>Internal Medicine Department 2,</p><p>Moscow</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гаврилов</surname><given-names>Ю. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Gavrilov</surname><given-names>Yu. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Никитин</surname><given-names>И. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Nikitin</surname><given-names>I. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кафедра госпитальной терапии № 2 лечебного факультета,</p><p>Москва</p></bio><bio xml:lang="en"><p>Internal Medicine Department 2,</p><p>Moscow</p></bio><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Федеральное государственное бюджетное образовательное учреждение Российский национальный исследовательский медицинский университет имени Н.И. Пирогова Министерства здравоохранения РФ; &#13;
Государственное учреждение здравоохранения Городская клиническая больница имени В.М. Буянова Департамента Здравоохранения Москвы</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Russian National Research Medical University n.a. N.I. Pirogov;&#13;
GBUZ «City Clinical Hospital № 12» of Healthcare Department of Moscow</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Государственное учреждение здравоохранения Городская клиническая больница имени В.М. Буянова Департамента Здравоохранения Москвы</institution><country>Россия</country></aff><aff xml:lang="en"><institution>GBUZ «City Clinical Hospital № 12» of Healthcare Department of Moscow</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Федеральное государственное бюджетное образовательное учреждение Российский национальный исследовательский медицинский университет имени Н.И. Пирогова Министерства здравоохранения РФ</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Russian National Research Medical University n.a. N.I. Pirogov</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2018</year></pub-date><pub-date pub-type="epub"><day>11</day><month>08</month><year>2018</year></pub-date><volume>8</volume><issue>4</issue><fpage>247</fpage><lpage>259</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Резник Е.В., Гаврилов Ю.В., Никитин И.Г., 2018</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="ru">Резник Е.В., Гаврилов Ю.В., Никитин И.Г.</copyright-holder><copyright-holder xml:lang="en">Reznik E.V., Gavrilov Y.V., Nikitin I.G.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.medarhive.ru/jour/article/view/803">https://www.medarhive.ru/jour/article/view/803</self-uri><abstract><p>Острая сердечная недостаточность и острая декомпенсация хронической сердечной недостаточности являются актуальными проблемами здравоохранения. Основные задачи ведения больных с этими состояниями включают достижение оптимального и стойкого разрешения застойных явлений, улучшение перфузии тканей, уменьшение выраженности клинической симптоматики, повышение переносимости физических нагрузок, качества жизни, предотвращение прогрессирования сердечной недостаточности, профилактику ухудшения функционального состояния органов-мишеней и развития осложнений, уменьшение частоты последующих декомпенсаций и госпитализаций, снижение внутрибольничной и постгоспитальной летальности. В лекции представлены основанные на современных международных и отечественных клинических рекомендациях алгоритмы диагностики, выделения клинических профилей пациентов, медикаментозного (включая диуретики, вазодилататоры, инотропные препараты, вазопрессоры, антикоагулянты и др.) и немедикаментозного (включая кислородотерапию, неинвазивную и инвазивную вентиляцию легких и др.) ведения больных с острой сердечной недостаточностью и острой декомпенсацией хронической сердечной недостаточности.</p></abstract><trans-abstract xml:lang="en"><p>Acute heart failure (AHF) and acute decompensation of chronic heart failure (ADHF) are urgent health problems. The main tasks of the managing the patients with these conditions include the achieving of optimal and stable resolution of edema and dyspnea, the tissue perfusion improving, the severity of clinical symptoms reducing, the exercise tolerance increasing, the progression of heart failure preventing, the preventing of the target organs dysfunction, complications, decompensations and hospitalizations, the increasing of survival and improving the quality of life. The algorithm for diagnosis, clinical patient profiles recognition, pharmacological (including diuretics, vasodilators, inotropes, vasopressors, anticoagulants, etc.) and non-pharmacological (including oxygen therapy, non-invasive and invasive ventilation, etc.) approaches to the management of AHF and ADHF are presented in accordance with contemporary guidelines.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>острая сердечная недостаточность</kwd><kwd>декомпенсация хронической сердечной недостаточности</kwd><kwd>острая декомпенсированная сердечная недостаточность</kwd><kwd>кардиогенный сердечная астма</kwd><kwd>отек легких</kwd><kwd>кардиогенный шок</kwd><kwd>кислородотерапия</kwd><kwd>искусственная вентиляция легких</kwd><kwd>инотропная поддержка</kwd><kwd>вазопрессоры</kwd><kwd>диуретики</kwd><kwd>ультрафильтрация</kwd><kwd>заместительная почечная терапия</kwd><kwd>найтрийуретические пептиды</kwd></kwd-group><kwd-group xml:lang="en"><kwd>acute heart failure</kwd><kwd>decompensation of chronic heart failure</kwd><kwd>acute decompensated heart failure</kwd><kwd>cardiogenic pulmonary edema</kwd><kwd>cardiogenic shock</kwd><kwd>oxygen therapy</kwd><kwd>invasive lung ventilation</kwd><kwd>inotropic support</kwd><kwd>vasopressors</kwd><kwd>diuretics</kwd><kwd>ultrafiltration</kwd><kwd>renal replacement therapy</kwd><kwd>natriu retic peptides</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Жусупова Г.К., Загоруля Н.Л., Альмухамедова А.Х. и др. Клинический протокол диагностики и лечения. Кардиогенный отек легких. 2016. [Электронный ресурс]. URL: https://diseases. medelement.com/disease/14929. (дата обращения: 04.07.2018). Zhusupova G.K., Zagorulya N.L., Almuhamedova A.H. Clinical Protocol of Diagnosis and Treatment. Cardiogenic pulmonary edema. 2016. [Electronic resource]. URL: https://diseases. medelement.com/disease/14929. (date of the application: 04.07.2018) [In Russian]</mixed-citation><mixed-citation xml:lang="en">Жусупова Г.К., Загоруля Н.Л., Альмухамедова А.Х. и др. Клинический протокол диагностики и лечения. Кардиогенный отек легких. 2016. [Электронный ресурс]. URL: https://diseases. medelement.com/disease/14929. (дата обращения: 04.07.2018). Zhusupova G.K., Zagorulya N.L., Almuhamedova A.H. Clinical Protocol of Diagnosis and Treatment. Cardiogenic pulmonary edema. 2016. [Electronic resource]. URL: https://diseases. medelement.com/disease/14929. (date of the application: 04.07.2018) [In Russian]</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Костенко А.А. Клинические рекомендации (протокол) по оказанию скорой медицинской помощи при кардиогенном шоке. 2014. [Электронный ресурс]. URL: https://health.admtyumen.ru/files/upload/OIV/D_zdr/docx. (дата обращения: 04.07.2018) Kostenko A.A. Clinical recommendations (protocol) for the provision of emergency medical care for cardiogenic shock. [Electronic resource]. URL: https://health.admtyumen.ru/files/upload/OIV/D_ zdr/docx. (date of the application: 04.07.2018) [In Russian]</mixed-citation><mixed-citation xml:lang="en">Костенко А.А. Клинические рекомендации (протокол) по оказанию скорой медицинской помощи при кардиогенном шоке. 2014. [Электронный ресурс]. URL: https://health.admtyumen.ru/files/upload/OIV/D_zdr/docx. (дата обращения: 04.07.2018) Kostenko A.A. Clinical recommendations (protocol) for the provision of emergency medical care for cardiogenic shock. [Electronic resource]. URL: https://health.admtyumen.ru/files/upload/OIV/D_ zdr/docx. (date of the application: 04.07.2018) [In Russian]</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Мареев В.Ю., Фомин И.В., Агеев Ф.Т. и др. Клинические рекомендации. Хроническая сердечная недостаточность (ХСН). Журнал сердечная недостаточность. 2017; 18(1): 3-40. Mareev V.Yu., Fomin I.V., Ageev F.T. et al. Clinical recommendations. Clinical recommendations. Chro nic heart failure (CHF). Journal of heart failure (Russian). 2017; 18(1): 3-40 [In Russian]</mixed-citation><mixed-citation xml:lang="en">Мареев В.Ю., Фомин И.В., Агеев Ф.Т. и др. Клинические рекомендации. Хроническая сердечная недостаточность (ХСН). Журнал сердечная недостаточность. 2017; 18(1): 3-40. Mareev V.Yu., Fomin I.V., Ageev F.T. et al. Clinical recommendations. Clinical recommendations. Chro nic heart failure (CHF). Journal of heart failure (Russian). 2017; 18(1): 3-40 [In Russian]</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Резник Е.В., Никитин И.Г. Алгори тм лечения больных с хронической сердечной недостаточностью с низкой фракцией выброса левого желудочка. Архивъ внутренней медицины. 2018; 8(2): 85-99. DOI: 10.20514/2226-6704-2018-8-2-85-99 Reznik E.V., Nikitin I.G. algorithm for the treatment of patients with chronic heart failure with reduced left ventricular ejection fraction. The Russian Archives of Internal Medicine. 2018; 8(2): 85-99. [In Russian]. DOI: 10.20514/2226-6704-2018-8-2-85-99</mixed-citation><mixed-citation xml:lang="en">Резник Е.В., Никитин И.Г. Алгори тм лечения больных с хронической сердечной недостаточностью с низкой фракцией выброса левого желудочка. Архивъ внутренней медицины. 2018; 8(2): 85-99. DOI: 10.20514/2226-6704-2018-8-2-85-99 Reznik E.V., Nikitin I.G. algorithm for the treatment of patients with chronic heart failure with reduced left ventricular ejection fraction. The Russian Archives of Internal Medicine. 2018; 8(2): 85-99. [In Russian]. DOI: 10.20514/2226-6704-2018-8-2-85-99</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Смирнов А.В., Добронравов В.А., Национальные рекомендации. Острое повреждение почек: основные принципы диагностики, профилактики и терапии. [Электронный ресурс]. URL: http://nonr.ru/wp-content/uploads/2013/11/ОСТРОЕПОВРЕЖДЕНИЕ-ПОЧЕК-ОСНОВНЫЕ-ПРИНЦИПЫДИАГНОСТИКИ-ПРОФИЛАКТИКИ-И-ТЕРАПИИ.pdf. 2015. (дата обращения: 04.07.2018) Smirnov A.V., Dobronravov V.A., National Recommendations. Acute renal damage: the basic principles of diagnosis, prevention and therapy. [Electronic resource]. URL: http://nonr.ru/wpcontent/uploads/2013/11/ОСТРОЕ-ПОВРЕЖДЕНИЕ-ПОЧЕКОСНОВНЫЕ-ПРИНЦИПЫ-ДИАГНОСТИКИ-ПРОФИЛАКТИКИИ-ТЕРАПИИ.pdf. 2015. (date of the application: 04.07.2018) [In Russian]</mixed-citation><mixed-citation xml:lang="en">Смирнов А.В., Добронравов В.А., Национальные рекомендации. Острое повреждение почек: основные принципы диагностики, профилактики и терапии. [Электронный ресурс]. URL: http://nonr.ru/wp-content/uploads/2013/11/ОСТРОЕПОВРЕЖДЕНИЕ-ПОЧЕК-ОСНОВНЫЕ-ПРИНЦИПЫДИАГНОСТИКИ-ПРОФИЛАКТИКИ-И-ТЕРАПИИ.pdf. 2015. (дата обращения: 04.07.2018) Smirnov A.V., Dobronravov V.A., National Recommendations. Acute renal damage: the basic principles of diagnosis, prevention and therapy. [Electronic resource]. URL: http://nonr.ru/wpcontent/uploads/2013/11/ОСТРОЕ-ПОВРЕЖДЕНИЕ-ПОЧЕКОСНОВНЫЕ-ПРИНЦИПЫ-ДИАГНОСТИКИ-ПРОФИЛАКТИКИИ-ТЕРАПИИ.pdf. 2015. (date of the application: 04.07.2018) [In Russian]</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Фомин И.В., Беленков Ю.Н., Мареев В.Ю., Распространенность ХСН в Европей-ской части Российской Федерации — данные ЭПОХА-ХСН. Сердечная недостаточность. 2006; 7(1): 4-8. Fomin I.V., Belenkov Yu.N., Mareyev V.Yu. Prevalence of CHF in the European part of the Russian Federation — data of EPOCHA-CHF. Heart failure. 2006; 7(1): 4-8 [In Russian].</mixed-citation><mixed-citation xml:lang="en">Фомин И.В., Беленков Ю.Н., Мареев В.Ю., Распространенность ХСН в Европей-ской части Российской Федерации — данные ЭПОХА-ХСН. Сердечная недостаточность. 2006; 7(1): 4-8. Fomin I.V., Belenkov Yu.N., Mareyev V.Yu. Prevalence of CHF in the European part of the Russian Federation — data of EPOCHA-CHF. Heart failure. 2006; 7(1): 4-8 [In Russian].</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Braunwald E. Heart failure. JACC. Heart Fail. 2013; 1(1): 1-20.</mixed-citation><mixed-citation xml:lang="en">Braunwald E. Heart failure. JACC. Heart Fail. 2013; 1(1): 1-20.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Braunwald E. The war against heart failure: the Lancet lecture. Lancet. 2015; 385 (9970): 812-24.</mixed-citation><mixed-citation xml:lang="en">Braunwald E. The war against heart failure: the Lancet lecture. Lancet. 2015; 385 (9970): 812-24.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Bueno H., Vranckx P., The Acute Cardiovascular Care Association Clinical Decision-Making Toolkit, As sociation, A.C.C., Editor. 2018. https://www.escardio.org/static_file/Escardio/Subspecialty/ACCA/TOOLKIT_V2.pdf (circulation date 17.05.2018)</mixed-citation><mixed-citation xml:lang="en">Bueno H., Vranckx P., The Acute Cardiovascular Care Association Clinical Decision-Making Toolkit, As sociation, A.C.C., Editor. 2018. https://www.escardio.org/static_file/Escardio/Subspecialty/ACCA/TOOLKIT_V2.pdf (circulation date 17.05.2018)</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Cheng J.M., den Uil C.A., Hoeks S.E. et al. Percutaneous left ventricular assist devices vs. intra-aortic balloon pump counterpulsation for treatment of cardiogenic shock: a metaanalysis of controlled trials. Eur. Heart J. 2009; 30(17): 2102-8.</mixed-citation><mixed-citation xml:lang="en">Cheng J.M., den Uil C.A., Hoeks S.E. et al. Percutaneous left ventricular assist devices vs. intra-aortic balloon pump counterpulsation for treatment of cardiogenic shock: a metaanalysis of controlled trials. Eur. Heart J. 2009; 30(17): 2102-8.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Conrad K.P. Maternal vasodilation in pregnancy: the emerging role of relaxin. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2011; 301(2): R267-75.</mixed-citation><mixed-citation xml:lang="en">Conrad K.P. Maternal vasodilation in pregnancy: the emerging role of relaxin. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2011; 301(2): R267-75.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Hummel S.L., Pauli N.P., Krumholz H.M. et al. Thirty-day outcomes in Medicare patients with heart failure at heart transplant centers. Circ. Heart Fail. 2010; 3(2): 244-52.</mixed-citation><mixed-citation xml:lang="en">Hummel S.L., Pauli N.P., Krumholz H.M. et al. Thirty-day outcomes in Medicare patients with heart failure at heart transplant centers. Circ. Heart Fail. 2010; 3(2): 244-52.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Jessup M., Drazner M.H., Book W. et al. 2017 ACC/AHA/HFSA/ISHLT/ACP Advanced Training Statement on Advanced Heart Failure and Transplant Cardiology (Revision of the ACCF/AHA/ACP/HFSA/ISHLT 2010 Clinical Competence Statement on Management of Pat ients With Advanced Heart Failure and Cardiac Transplant): A Report of the ACC Competency Management Committee. Circ. Heart Fail. 2017; 10 (6).</mixed-citation><mixed-citation xml:lang="en">Jessup M., Drazner M.H., Book W. et al. 2017 ACC/AHA/HFSA/ISHLT/ACP Advanced Training Statement on Advanced Heart Failure and Transplant Cardiology (Revision of the ACCF/AHA/ACP/HFSA/ISHLT 2010 Clinical Competence Statement on Management of Pat ients With Advanced Heart Failure and Cardiac Transplant): A Report of the ACC Competency Management Committee. Circ. Heart Fail. 2017; 10 (6).</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Maggioni A.P., Dahlstrom U., Filippatos G. et al. EURObservational Research Programme: regional differences and 1-year follow-up results of the Heart Failure Pilot Survey (ESC-HF Pilot). Eur. J. Heart Fail. 2013; 15(7): 808-17.</mixed-citation><mixed-citation xml:lang="en">Maggioni A.P., Dahlstrom U., Filippatos G. et al. EURObservational Research Programme: regional differences and 1-year follow-up results of the Heart Failure Pilot Survey (ESC-HF Pilot). Eur. J. Heart Fail. 2013; 15(7): 808-17.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Mebazaa A., Yilmaz M.B., Levy P. et al. Recommendations on prehospital and early hospital man agement of acute heart failure: a consensus paper from the Heart Failure Association of the European Society of Cardiology, the European Society of Emergency Medicine and the Society of Academic Emergency Medicine-short version. Eur. Heart J. 2015; 36(30): 1958-66.</mixed-citation><mixed-citation xml:lang="en">Mebazaa A., Yilmaz M.B., Levy P. et al. Recommendations on prehospital and early hospital man agement of acute heart failure: a consensus paper from the Heart Failure Association of the European Society of Cardiology, the European Society of Emergency Medicine and the Society of Academic Emergency Medicine-short version. Eur. Heart J. 2015; 36(30): 1958-66.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">O’Neill W.W., Kleiman N.S., Moses J. et al. A prospective, randomized clinical trial of hemodynamic support with Impella 2.5 versus intra-aortic balloon pump in patients undergoing highrisk percutaneous coronary intervention: the PROTECT II study. Circulation. 2012; 126(14): 1717-27.</mixed-citation><mixed-citation xml:lang="en">O’Neill W.W., Kleiman N.S., Moses J. et al. A prospective, randomized clinical trial of hemodynamic support with Impella 2.5 versus intra-aortic balloon pump in patients undergoing highrisk percutaneous coronary intervention: the PROTECT II study. Circulation. 2012; 126(14): 1717-27.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Ponikowski P., Voors A.A., Anker S.D. et al. 2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure: The Task Force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC)Developed with the special contribution of the Heart Failure Association (HFA) of the ESC. Eur. Heart J. 2016; 37(27): 2129-2200.</mixed-citation><mixed-citation xml:lang="en">Ponikowski P., Voors A.A., Anker S.D. et al. 2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure: The Task Force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC)Developed with the special contribution of the Heart Failure Association (HFA) of the ESC. Eur. Heart J. 2016; 37(27): 2129-2200.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Riebandt J., Haberl T., Mahr S. et al. Preoperative patient optimization using extracorporeal life support improves outcomes of INTERMACS Level I patients receiving a permanent ventricular assist device. Eur. J. Cardiothorac. Surg. 2014; 46(3): 486-92; discussion 492.</mixed-citation><mixed-citation xml:lang="en">Riebandt J., Haberl T., Mahr S. et al. Preoperative patient optimization using extracorporeal life support improves outcomes of INTERMACS Level I patients receiving a permanent ventricular assist device. Eur. J. Cardiothorac. Surg. 2014; 46(3): 486-92; discussion 492.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Ross J.S., Chen J., Lin Z. et al. Recent national trends in readmission rates after heart failure hospitalization. Circ. Heart Fail. 2010; 3(1): 97-103.</mixed-citation><mixed-citation xml:lang="en">Ross J.S., Chen J., Lin Z. et al. Recent national trends in readmission rates after heart failure hospitalization. Circ. Heart Fail. 2010; 3(1): 97-103.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Stewart S., Blue L., Walker A. et al. An economic analysis of specialist heart failure nurse management in the UK; can we afford not to implement it? Eur. Heart J. 2002; 23(17): 1369-78.</mixed-citation><mixed-citation xml:lang="en">Stewart S., Blue L., Walker A. et al. An economic analysis of specialist heart failure nurse management in the UK; can we afford not to implement it? Eur. Heart J. 2002; 23(17): 1369-78.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Teerlink, J.R., Cotter, G., Davison, B.A. et al., Serelaxin, recombinant human relaxin-2, for treatment of acute heart failure (RELAXAHF): a randomised, placebo-controlled trial. Lancet. 2013; 381 (9860): 29-39.</mixed-citation><mixed-citation xml:lang="en">Teerlink, J.R., Cotter, G., Davison, B.A. et al., Serelaxin, recombinant human relaxin-2, for treatment of acute heart failure (RELAXAHF): a randomised, placebo-controlled trial. Lancet. 2013; 381 (9860): 29-39.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Yancy C.W., Jessup M., Bozkurt B. et al. 2017 ACC/AHA/HFSA Focused Update of the 2013 ACCF/AHA Guideline for the Management of Heart Failure: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Failure Society of America. Circulation. 2017; 136(6): e137-e161.</mixed-citation><mixed-citation xml:lang="en">Yancy C.W., Jessup M., Bozkurt B. et al. 2017 ACC/AHA/HFSA Focused Update of the 2013 ACCF/AHA Guideline for the Management of Heart Failure: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Failure Society of America. Circulation. 2017; 136(6): e137-e161.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
