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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">avk</journal-id><journal-title-group><journal-title xml:lang="ru">Архивъ внутренней медицины</journal-title><trans-title-group xml:lang="en"><trans-title>The Russian Archives of Internal Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2226-6704</issn><issn pub-type="epub">2411-6564</issn><publisher><publisher-name>“SINAPS” LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20514/2226-6704-2019-9-6-467-474</article-id><article-id custom-type="elpub" pub-id-type="custom">avk-986</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>РАЗБОР КЛИНИЧЕСКИХ СЛУЧАЕВ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ANALYSIS OF CLINICAL CASES</subject></subj-group></article-categories><title-group><article-title>Первичные лимфомы головного мозга. Психические нарушения после биопсии (описание случая)</article-title><trans-title-group xml:lang="en"><trans-title>Primary cerebral lymphoma. Mental disorders after biopsy (case report)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ильяев</surname><given-names>Н. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Ilyaev</surname><given-names>N. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Максакова</surname><given-names>О. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Maksakova</surname><given-names>O. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Зайцев</surname><given-names>О. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Zaitsev</surname><given-names>O. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Олег Семенович Зайцев</p><p>Москва, Н. Новгород</p></bio><bio xml:lang="en"><p>Oleg S. Zaitsev</p><p>Moscow, N. Novgorod</p></bio><email xlink:type="simple">OZaitsev@nsi.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Пицхелаури</surname><given-names>Д. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Pitskhelauri</surname><given-names>D. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Троицкий</surname><given-names>А. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Troitskiy</surname><given-names>A. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кобяков</surname><given-names>Г. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Kobiakov</surname><given-names>G. L.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Поддубский</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Poddubskiy</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Маряшев</surname><given-names>С. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Maryashev</surname><given-names>S. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Быканов</surname><given-names>А. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Bykanov</surname><given-names>A. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГАУ «НМИЦ нейрохирургии им. Н.Н. Бурденко» Минздрава РФ</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal State Autonomous Institution National Medical Research Center for Neurosurgery Named After N.N. Burdenko</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГАУ «НМИЦ нейрохирургии им. Н.Н. Бурденко» Минздрава РФ; Приволжский исследовательский медицинский университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal State Autonomous Institution National Medical Research Center for Neurosurgery Named After N.N. Burdenko; Privolzhsky Research Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>30</day><month>11</month><year>2019</year></pub-date><volume>9</volume><issue>6</issue><fpage>467</fpage><lpage>474</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Ильяев Н.П., Максакова О.А., Зайцев О.С., Пицхелаури Д.И., Троицкий А.П., Кобяков Г.Л., Поддубский А.А., Маряшев С.А., Быканов А.Е., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Ильяев Н.П., Максакова О.А., Зайцев О.С., Пицхелаури Д.И., Троицкий А.П., Кобяков Г.Л., Поддубский А.А., Маряшев С.А., Быканов А.Е.</copyright-holder><copyright-holder xml:lang="en">Ilyaev N.P., Maksakova O.A., Zaitsev O.S., Pitskhelauri D.I., Troitskiy A.P., Kobiakov G.L., Poddubskiy A.A., Maryashev S.A., Bykanov A.E.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.medarhive.ru/jour/article/view/986">https://www.medarhive.ru/jour/article/view/986</self-uri><abstract><p>В статье приведен обзор литературы по диагностике и лечению первичных лимфом центральной нервной системы и описан случай развития психических нарушений до и после операции у пациентки с диагнозом лимфома III желудочка головного мозга. Благодаря междисциплинарному подходу психопатологическая динамика анализировалась с учетом структурно-функционального состояния головного мозга, что позволило уточнить возможные причины ее возникновения и способы лечения. Острый дебют заболевания в виде спутанности и головной боли был связан с затруднением ликворотока, обусловленным локализацией опухоли. Причиной дезинтеграции сознания в послеоперационном периоде явилась гипоксия мозга и вызванная ей нестабильность связей между церебральными структурами. Своеобразие процесса восстановления сознания могло определяться преморбидными личностными особенностями.</p></abstract><trans-abstract xml:lang="en"><p>The article reviews the literature on the diagnosis and treatment of primary lymphomas of the central nervous system and describes a case of mental disorder before and after surgery in a patient with lymphoma of the third ventricle. Using an interdisciplinary approach, psychopathological dynamics is analyzed taking into account the structural and functional state of the brain, which allowed to clarify the possible causes of mental disorders and methods of treatment. Acute onset of confusion and headache was associated with disorders of the liquor outflow, due to the localization of the tumor. The reason for the disintegration of consciousness after surgery was brain hypoxia and the instability of connections between cerebral structures associated with it. The peculiarity of the consciousness recovery could be determined by premorbid personal traits.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>лимфома головного мозга</kwd><kwd>третий желудочек мозга</kwd><kwd>биопсия</kwd><kwd>дезинтеграция сознания</kwd><kwd>психические нарушения</kwd><kwd>психопатология</kwd><kwd>психофармакотерапия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>brain lymphoma</kwd><kwd>third brain ventricle</kwd><kwd>biopsy</kwd><kwd>disintegration of consciousness</kwd><kwd>mental disorders</kwd><kwd>psychopathology</kwd><kwd>psychopharmacotherapy</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Villano J.L., Koshy M., Shaikh H. et al. Age, gender, and racial differences in incidence and survival in primary CNS lymphoma. 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