Patients with cardiovascular diseases and NSAIDs use: real clinical practice

Objective — to study the frequency and characteristics of the use of nonsteroidal anti-inflammatory drugs (NSAIDs) in patients with cardiovascular diseases hospitalized in the emergency departments of cardiology. Materials and methods. Examined 190 patients hospitalized in the emergency cardiology departments of the State Healthcare Institution Regional Clinical Hospital of Saratov from January to March 2020. The study was continuous, a questionnaire was conducted for all patients hospitalized during the specified period. The study involved 103 (54%) men and 87 women, the average age of the patients was 62.05 ± 11.11 years. The reason for hospitalization in most patients was acute coronary pathology — 116 (61%) patients, 34 (18%) patients — decompensated heart failure, 21 (11%) patients — various rhythm disturbances; in 15 (8%) patients — hypertensive crisis against the background of uncontrolled arterial hypertension, in 4 (2%) patients — pulmonary embolism. Results. During the last month, 92 (48%) patients took NSAIDs for various reasons: 42 men (46%) and 50 women (54%). The average age of patients taking NSAIDs is higher than that of patients who did not take NSAIDs (63.98 ± 11.62 years and 60.20 ± 10.27 years, respectively, p = 0.018). Among patients forced to take NSAIDs over the past month, joint pain — 43 (47%) patients, headache — 40 (43%) patients, back pain — 30 (33%) were indicated as the main cause or one of the reasons sick. In 15 (16%) patients, the reason for taking NSAIDs was toothache, in 14 (15%) patients — chest pain, musculoskeletal pain — in 11 patients (12%). Several reasons for taking NSAIDs were indicated by 40 (43%) patients, the majority — a combination of joint pain and back pain. Conclusion. Almost half of patients admitted to emergency cardiology departments had taken NSAIDs in the previous month. Most patients have to take NSAIDs often, regularly, for a long time. More than a third of the examined patients used various methods of drug administration, including unreasonably frequent and prolonged parenteral use or the simultaneous use of various methods of administration of various drugs.

cardiovascular diseases, nonsteroidal anti-inflammatory drugs

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