REPERFUSION MYOCARDIAL INJURY AFTER PRIMARY PERCUTANEOUS CORONARY INTERVENTION IN PATIENT WITH ACUTE ST-ELEVATION MYOCARDIAL INFARCTION. CLINICAL OBSERVATION
https://doi.org/10.20514/2226-6704-2016-6-6-65-67
Abstract
The goal is to determine the possibilities of treatment of reperfusion myocardial injury in patient with acute ST-elevation myocardial infarction after percutaneous coronary intervention. Methods. Clinical observation. Results and discussion. After percutaneous coronary intervention the return of blood flow can result in reperfusion myocardial ischemia, «no-reflow» phenomenon, which is manifested with recurrent angina, disturbances of rhythm and conduction, worsening of ECG, decrease in local and global contractility of the left ventricular myocardium. Conclusion. The addition of calcium channel blockers to standard therapy can stabilize the patients condition, relief angina.
About the Authors
N. A. Kosheleva
State Educational Institution of High Professional Education «Saratov State Medical University n.a. V.I. Razumovsky» based on State
healthcare facility «Saratov Regional Clinical Hospital» of Ministry of Health and Social Development of Saratov Region, Saratov, Russia
Russian Federation
Russian Federation
N. A. Magdeeva
State Educational Institution of High Professional Education «Saratov State Medical University n.a. V.I. Razumovsky» based on State
healthcare facility «Saratov Regional Clinical Hospital» of Ministry of Health and Social Development of Saratov Region, Saratov, Russia
Russian Federation
Russian Federation
V. V. Phrontaseva
State Educational Institution of High Professional Education «Saratov State Medical University n.a. V.I. Razumovsky» based on State
healthcare facility «Saratov Regional Clinical Hospital» of Ministry of Health and Social Development of Saratov Region, Saratov, Russia
Russian Federation
Russian Federation
O. S. Lobanova
State Educational Institution of High Professional Education «Saratov State Medical University n.a. V.I. Razumovsky» based on State
healthcare facility «Saratov Regional Clinical Hospital» of Ministry of Health and Social Development of Saratov Region, Saratov, Russia
Russian Federation
Russian Federation
Z. B. Hashucaeva
State Educational Institution of High Professional Education «Saratov State Medical University n.a. V.I. Razumovsky» based on State
healthcare facility «Saratov Regional Clinical Hospital» of Ministry of Health and Social Development of Saratov Region, Saratov, Russia
Russian Federation
Russian Federation
References
1. Гречешкин А.А., Майнгарт С.В., Пахолков А.Н. Актуальность проблемы реперфузионного повреждения миокарда при первичном чрескожном коронарном вмешательстве. Эндоваскулярная хирургия. 2015; 1-2: 20-29.
2. Grecheshkin A.A., Mayngart S.V., Pakholkov A.N. Aktualnost of a problem of reperfusion injury of a myocardium at primary chreskozhny coronary intervention. Endovascular surgery. 2015; 1-2: 20-29 [in Russian].
3. Bаigent С., Сollins R., Pаrish S., Sleight P., Peto R. ISIS-2: 10 yeаr survivаl among pаtients with suspected аcute myoсаrdial infarсtion in rаndomized compаrison of intravenous streptokinаse, orаl аspirin, bоth, оr nеithеr. The ISIS 2 (Sеcоnd Internаtiоnаl Study of Infаrсt Survivаl) Соllаbоrаtivе Grоup. BMJ (Clinicаl research ed). 1998; 316(7141): 1337-1343.
4. Gаliutano L., Lоmbardo А., Mаseri А. et al. Тemparal evоlution and functiоnal outcоme of no reflow: sustаined and spоntaneously rеversible pаtterns follоwing succеssful coronаryrecanаlization. Heart. 2003; 89: 731-737.
5. Hаusenlоy D.J., Bаxter G., Bеll R. et al. Trаnslating nоvel cаrdiоprotectiоn: the Hаtter Worshоp Recommеndation. Bаsic Res. Cаrdiol. 2010; 105: 677-686.
6. Hеnriques J., Zijlstrа F., Ottervаnger J. et al. Incidеnce and clinicаl significаnce of distаlembolization during primаry angiоplasty fоr аcute myоcаrdial infarctiоn. Eur. Heаrt J. 2002; 23: 1112-1117.
7. Kеeley E.C., Bоura J.A., Grinеs C.L. Primеry angioplasty versus intrаvenous thrombоlytic therаpy fоr аcute myоcardial infаrction: a quаntitative reviеw of 23 rаndomized trials. Lаncet. 2003; 361(9351): 13-20.
8. Tаniyamа Y., Ito H., Iwаkura K. et al. Beneficiаl effect corоnary verаpamil on micrоvasculer and myоcardial pаtients with аcute myоcardial infаrction. J. Am. Cor. 1997; 30:1193-1199.
9. Vаn Wаgonеr D.R., Bоnd M. Repеrfusion arrhythmiаs: nеw insights intо the rоle of the Na+/Ca2+ exchаnger. J. Moll. Cell. Cardiol. 2001; 33: 2071-2074.
10. Yаng X. M., Philipp S., Downеy J. M., Cоhen M. V. Pоstconditiоning’s prоtection is not depеndent on circulаting bloоd factors or cеlls but invоlves adenоsine recеptors and requirеs PI3-kinаse and guаnylyl cyclаse аctivation. Bаsic Res. Cardiol. 2005; 100: 57–63.
Review
For citations:
Kosheleva N.A., Magdeeva N.A., Phrontaseva V.V., Lobanova O.S., Hashucaeva Z.B. REPERFUSION MYOCARDIAL INJURY AFTER PRIMARY PERCUTANEOUS CORONARY INTERVENTION IN PATIENT WITH ACUTE ST-ELEVATION MYOCARDIAL INFARCTION. CLINICAL OBSERVATION. The Russian Archives of Internal Medicine. 2016;6(6):65-67. (In Russ.) https://doi.org/10.20514/2226-6704-2016-6-6-65-67
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