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LYELL`S SYNDROME. PRACTICAL CASE

https://doi.org/10.20514/2226-6704-2018-8-3-231-236

Abstract

In the article the interdisciplinary problem of drug allergy being analysed, namely its systemic symptoms. There have been shown the variants of systemic allergic reactions and the characteristics of the toxic epidermal necrolysis or Lyell`s syndrome as one of the most serious and rare form of illness. There has been carried out the analysis of the clinical case of the Lyell`s syndrome with diagnostic difficulties in the beginning phase of the disease and favorable outcome. There has been proved the dynamics of clinical signs and their reversed development.

About the Authors

Z. A. Khokhlova
Novokuznetsk State Institute of Advanced Medical Education — the branch office of FGBOU DPO RMANPO of the Russian Federation Ministry of Health, Novokuznetsk
Russian Federation
Infectious Diseases Department, Dermatovenerology Depertment


R. A. Gileva
Novokuznetsk State Institute of Advanced Medical Education — the branch office of FGBOU DPO RMANPO of the Russian Federation Ministry of Health, Novokuznetsk
Russian Federation
Infectious Diseases Department, Dermatovenerology Depertment


I. G. Konyakhina
Novokuznetsk State Institute of Advanced Medical Education — the branch office of FGBOU DPO RMANPO of the Russian Federation Ministry of Health, Novokuznetsk
Russian Federation
Infectious Diseases Department, Dermatovenerology Depertment


A. P. Tishkina
GBUZ KO «Novokuznetsk Municipal Clinical Infectious Diseases Hospital № 8», Novokuznetsk
Russian Federation


References

1. Khaitov P.M. Allergology and immunology. М.: GEOTAR — Media. 2009; 656 р. [in Russian].

2. Medicinal allergy. Methodical recommendations for doctors. Edited by Academician RAS and RAMS R.M. Haitova. Farmarus print media. M. 2012; 75 р. [in Russian].

3. Federal clinical recommendations on patients with Steven-Johnson Syndrome/toxic epidermal necrolysis. Russian Dermatovenerologists and Cosmetologists Society. М. 2015; 11 р. [in Russian].

4. Tezyaeva S.A., Mlinnik R.A., Degtyareva S.F. and et al. Lyell’s Syndrome as a rare complication of drug therapy (clinical cases). Medial’. 2015; 2 (16): 42-45 [in Russian].

5. Chicherina E.N., Malykh S.V., Akshentseva M.V. Lyell’s Syndrome (clinical picture, diagnostics, modern methods of treatment). Vyatka Medical Herald. 2008; 3-4:15-19 [in Russian].


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For citations:


Khokhlova Z.A., Gileva R.A., Konyakhina I.G., Tishkina A.P. LYELL`S SYNDROME. PRACTICAL CASE. The Russian Archives of Internal Medicine. 2018;8(3):231-236. https://doi.org/10.20514/2226-6704-2018-8-3-231-236

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ISSN 2226-6704 (Print)
ISSN 2411-6564 (Online)