FREQUENCY OF OCCURRENCE OF RISK FACTORS AND ADHERENCE TO DRUG THERAPY IN YAKUTS WHO UNDERWENT Q-POSITIVE MYOCARDIAL INFARCTION
https://doi.org/10.20514/2226-6704-2018-8-4-291-299
Abstract
The aim of the article was to study for 12 months the adherence to drug therapy and the incidence of cardiovascular risk factors in Yakutia patients who underwent Q-positive myocardial infarction.
Materials and methods. The analysis included 113 patients from Yakutsk with Q-positive acute myocardial infarction, the average age is 59 [51;64] years old.
Results. The following conclusions are obtained: The majority of patients of Yakut nationality who underwent Q-positive myocardial infarction have a high incidence of cardiovascular risk factors. Among the examined patients of this category after 6 months was received a low adherence to prescription drugs: clopidogrel /ticagrelor (by 9.9%), ACE inhibitors / sartans (by 18%), β-adrenoblockers (by 24.6%), statins (by 46.7%). For the 12th month after a second consultation, there was an increased adherence to taking the statins by 33.3% and beta-blockers by 17.8%. AH is a well-controlled risk factor, in most patients there is an effective reduction in high blood pressure values from the first months. The mean of total cholesterol, cholesnerol — LDL and the frequency of hypercholesterinemia, hypercholesterinemia LDL for 12 months after a recent MI is decreased, but the target values were not achieved due to low adherence to taking statins.
Conclusion. Due to the low adherence to drug therapy and the insufficient correction of risk factors for CVD after MI there was noted repeated hospitalizations for repeated ACS, decompensation of CHF, and fatal cases/outcomes, regardless of ethnicity, which requires intensification of the measures for dispenserization, at the primary level health.
About the Authors
E. S. KylbanovaRussian Federation
Yakutsk
E. V. Guryeva
Russian Federation
Yakutsk
A. V. Pavlova
Russian Federation
Yakutsk
References
1. Алексеев В.П., Иванов К.И., Константинов В.В., Жданов В.С., Акимов А.И., Осипова О.Н., Кривошапкин В.Г. Эпидемиология ишемической болезни сердца и особенности атеросклероза у мужчин Якутска. Терапевтический архив. 2001; 73(1): 12-18. Alekseev V.P., Ivanov K.I., Konstantinov V.V. et al. Epidemiology of ischemic heart disease and peculiarities of atherosclerosis in male residents of Yakutsk. Therapeutic archive. 2001; 73(1): 12-18 [In Russian].
2. Рекомендации экспертов Всероссийского научного общества кардиологов по диагностике и лечению метаболического синдрома. Второй пересмотр. Практическая медицина. 2010; 5(44): 81-101 Recommendations of the experts of the All-Russian Scientific Society of Cardiologists on Diagnosis and Treatment of Metabolic Syndrome. The second revision. Practical medicine. 2010; 5 (44): 81-101 [In Russian].
3. Диагностика и коррекция нарушений липидного обмена с целью профилактики и лечения атеросклероза: Российские рекомендации VI пересмотра. 2017; 3: 6-22. Diagnosis and correction of lipid metabolism disorders for the prevention and treatment of atherosclerosis: Russian recommendations of the VI revision. 2017; 3: 6-22 [In Russian].
4. Диагностика и коррекция нарушений липидного обмена с целью профилактики и лечения атеросклероза Российские рекомендации V пересмотр. Российское кардиологическое общество (РКО). Национальное Общество по изучению Атеросклероза (НОА). Российское общество кардиосоматической реабилитации и вторичной профилактики (РосОКР). Российский кардиологический журнал. 2012; 4(96): 32 с. Diagnosis and correction of lipid metabolism disorders in order to prevent and treat atherosclerosis. Russian recommendations V revision. Russian Cardiology Society. National Society for the Study of Atherosclerosis (NOA). Russian Society of Cardiosomal Rehabilitation and Secondary Prevention (RosOKR). Russian Cardiology Journal. 2012; 4(96): 32 p. [In Russian].
5. Климова Т.М., Федорова В.И., Балтахинова М.Е., Кривошапкин В.Г. Липидный профиль и дислипопротеинемии у коренного сельского населения Якутии. Сибирский медицинский журнал. 2012; 27(3): 142-146. Klimova T.M., Fedorova V.I., Baltahinova M.E. and others. Lipid profile and dyslipoproteinemia in the indigenous rural population of Yakutia. Siberian Medical Journal. 2012; 27(3): 142-146 [In Russian].
6. Кулешова Э.В., Панов А.В. Лечение и вторичная профилактика после инфаркта миокарда. Медицинский совет. 2014; 4: 39. Kuleshova E.V., Panov A.V. Treatment and secondary prevention after myocardial infarction. — Medical advice. 2014; 4: 39 [In Russian].
7. Оганов Р.Г. Статины — препараты первой линии в профилактике и лечении атеросклероза. Медицинский алфавит. 2013; 1(4): 12-15. Oganov R.G. Statins — first-line drugs in the prevention and treatment of atherosclerosis. Medical alphabet. 2013; 1(4): 12-15 [In Russian].
8. Рекомендации по диабету, предиабету и сердечно-сосудистым заболеваниям. Российский кардиологический журнал. 2014; 3 (107): 7-61. Recommendations for diabetes, prediabetes and cardiovascular diseases. Russian Cardiology Journal. 2014; 3 (107): 7-61 [In Russian].
9. Руда М.Я. Острый коронарный синдром: система организации лечения. Кардиология. 2011; 3: 4-9. Ruda M.Y. Acute coronary syndrome: the system of treatment organization. Cardiology. 2011; 3: 4-9 [In Russian].
10. Федорова В.И., Климова Т.М., Балтахинова М.Е., Кривошапкин В.Г. Артериальное давление и ожирение среди сельской коренной популяции. Якутский медицинский журнал. 2014; 1 (45): 4-6. Fedorova V.I., Klimova T.M., Baltahinova M.E., Krivoshapkin V.G. Arterial pressure and obesity among the rural indigenous population. Yakut medical journal. 2014; 1 (45): 4-6 [In Russian].
11. Шпектор А., Васильева Е. Современные подходы к вторичной профилактике острого инфаркта миокарда. Креативная кардиология. 2014; 2: 71-80. Shpektor A., Vasilieva E. Modern approaches to secondary prevention of acute myocardial infarction. Creative Cardiology. 2014; 2: 71-80 [In Russian].
12. Эрлих А.Д. Результаты шестимесячного наблюдения за больными с острыми коронарными синдромами в Российском регистре РЕКОРД. Кардиология. 2011; 12: 11-16. Erlich AD Results of a six-month observation of patients with acute coronary syndromes in the Russian registry RECORD. Cardiology. 2011; 12: 11-16 [In Russian].
13. Эрлих А.Д. Грацианский Н.А. и участники регистра РЕКОРД. Регистр острых коронарных синдромов РЕКОРД. Характеристика больных и лечение до выписки из стационара. Кардиология. 2009; 7: 4-12. Erlich A.D. Gratsiansky N.A. and participants in the RECORD register. Register of acute coronary syndromes RECORD. Characteristics of patients and treatment before discharge from the hospital. Cardiology. 2009; 7: 4-12 [In Russian].
14. Bonow R., Mann D., Zipes D., Libby P. et al. Braunwald’s heart disease: a textbook of cardiovascular medicine, 9th ed. Philadelphia: SaundersElseiver; 2012.
15. Spertus J.A., Masoudi F.A., Reid K.J., Peterson E.D., Magid D.J., Krumholz H.M. Impact of medication therapy discontinuation on mortality after myocardial infarction. Arch. Intern. Med. 2006; 166(17): 1842-7.
Review
For citations:
Kylbanova E.S., Guryeva E.V., Pavlova A.V. FREQUENCY OF OCCURRENCE OF RISK FACTORS AND ADHERENCE TO DRUG THERAPY IN YAKUTS WHO UNDERWENT Q-POSITIVE MYOCARDIAL INFARCTION. The Russian Archives of Internal Medicine. 2018;8(4):291-299. https://doi.org/10.20514/2226-6704-2018-8-4-291-299