New Coronavirus Infection (Covid-19): Clinical and Epidemiological Aspects

Environmental change, climate warming, population density increase, high migration activity of the population and other factors provoke the emergence and spread of new infections around the world. The emergence in December 2019 of diseases caused by the new coronavirus («coronavirus disease 2019») has already gone down in history as an emergency of international importance. It is known that the most common clinical manifestation of a new infection is pneumonia, and also in a significant part of patients — respiratory distress syndrome. Our article provides a brief analytical review of these temporary guidelines Ministry of Health of the Russian Federation «Prevention, Diagnosis and Treatment of a New Coronavirus Infection (COVID-19)», version 3 (03.03.20) and other published sources. The team of authors expresses the hope that these data will be useful to doctors in providing medical care to patients with a new coronary virus infection, as well as to teachers in preparing students and residents. Source: Ministry of Health of the Russian Federation. Temporary guidelines «Prevention, diagnosis and treatment of new coronavirus infection (COVID-19)», version 4 (27.03.20). Available on: https://static-3.rosminzdrav.ru/system/attachments/attaches/000/049/881/original/COVID19_recomend_v4.pdf   

1. World Health Organization. Clinical guidelines for the management of patients with severe acute respiratory infections with suspected infection with a new coronavirus (2019-nCoV). Temporary recommendations. Publication Date: January 25, 2020. [Electronic resource]. URL: http://www.euro.who.int/__data/assets/pdf_file/0020/426206/RUS-Clinical-Management-ofNovel_CoV_Final_without-watermark.pdf?ua=1. (date of the application: 23.03.2020) [In Russian]

2. Coronavirus (Covid-19). [Electronic resource]. URL: https://coronavirusmonitor.ru. (date of the application: 23.03.2020) [In Russian]

3. Alserehi H., Wali G., Alshukairi A., Alraddadi B. Impact of Middle East respiratory syndrome coronavirus (MERS-CoV) on pregnancy and perinatal outcome. BMC Infect Dis. 2016; 16: 105-108.

4. Bassetti M. The Novel Chinese Coronavirus (2019-nCoV) Infections: challenges for fighting the storm. https://doi.org/10.1111/eci.13209 URL: https://onlinelibrary.wiley.com/doi/abs/10.1111/eci.13209

5. Gu J., Han B., Jian Wang J. COVID-19: Gastrointestinal manifestations and potential fecal-oral transmission. Gastroenterology. 2020. https://doi.org/10.1053/j.gastro.2020.02.054

6. Cao B., Wang Y., Wen D. et al. A Trial of Lopinavir–Ritonavir in Adults Hospitalized with Severe Covid-19. New England Jurnal Medicine. 2020; DOI: 10.1056/NEJMoa2001282.

7. Zhang L., Lin D., Sun X. et al. Crystal structure of SARS-CoV-2 main protease provides a basis for design of improved α-ketoamide inhibitors. Science. 2020. doi. 10.1126/science.abb3405.

8. Federal Service for Supervision of Consumer Rights Protection and Human Well-Being. About a new coronavirus infection. [Electronic resource]. URL: https://rospotrebnadzor.ru/region/korono_virus/punkt.php. (date of the application: 23.03.2020) [In Russian]