New Diagnostic Possibilities for Determining the Activity of Ulcerative Colitis: The Role of Neutrophils
https://doi.org/10.20514/2226-6704-2022-12-4-285-292
Abstract
The incidence of ulcerative colitis has been increasing in recent years, and its manifestation at a young age has become a trend that is prognostically unfavorable. The clinical picture of ulcerative colitis is often vague, which leads to an initially erroneous diagnosis. One of the main problems is to assess the effectiveness of treatment and the risk of recurrence of ulcerative colitis, which requires invasive intervention. The aim of the study was to analyze the data of modern scientific literature on noninvasive biomarkers of ulcerative colitis. The data of foreign and domestic articles on the research topic published in Pubmed and eLibrary over the past 5-10 years are analyzed. Biomarkers of neutrophil origin are a promising direction in the primary diagnosis and assessment of ulcerative colitis activity.
About the Authors
E. V. Bolotova
State budgetary educational institution of higher professional education «Kuban state medical university» Ministry of health of the Russian Federation
Russian Federation
Russian Federation
Krasnodar
K. A. Yumukyan
State budgetary educational institution of higher professional education «Kuban state medical university» Ministry of health of the Russian Federation; State Public Health Budget Institution Scientific Research Institute — Ochapovsky Regional Clinic Hospital of Krasnodar Region Public Health Ministry
Russian Federation
Russian Federation
Krasnodar
A. V. Dudnikova
State budgetary educational institution of higher professional education «Kuban state medical university» Ministry of health of the Russian Federation
Russian Federation
Russian Federation
Krasnodar
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For citations:
Bolotova E.V., Yumukyan K.A., Dudnikova A.V. New Diagnostic Possibilities for Determining the Activity of Ulcerative Colitis: The Role of Neutrophils. The Russian Archives of Internal Medicine. 2022;12(4):285-292. https://doi.org/10.20514/2226-6704-2022-12-4-285-292
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