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Pulmonary Langerhans Cell Hysiocytosis: A Rare Pathology in The Practice of a Pulmonologist

https://doi.org/10.20514/2226-6704-2025-15-6-461-467

EDN: FNRNFA

Abstract

Pulmonary Langerhans cell histiocytosis is a rare disease with insidious onset and nonspecific manifestations. The article discusses two clinical cases of patients with a rare pathology — pulmonary histiocytosis from Langerhans cells. Young patients and smokers are described. The diagnosis was verified morphologically. In the first case, positive X–ray dynamics was noted against the background of smoking cessation, in the second case, the patient did not stop smoking, due to the severity of shortness of breath, changes in computed tomography of the lungs, prednisone was prescribed. Against this background, there was no significant positive trend.

About the Authors

E. S. Rvanina
Saratov State Medical University named after V.I. Razumovsky, Ministry of Health of the Russian Federation
Russian Federation

Ekaterina S. Rvanina — resident of the 1st training, Department of Hospital Therapy, Faculty of Medicine

Saratov 


Competing Interests:

The authors declare no conflict of interests 



N. A. Karoli
Saratov State Medical University named after V.I. Razumovsky, Ministry of Health of the Russian Federation
Russian Federation

Nina A. Karoli — professor of hospital therapy department of general medicine Department

Saratov 


Competing Interests:

The authors declare no conflict of interests 



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Review

For citations:


Rvanina E.S., Karoli N.A. Pulmonary Langerhans Cell Hysiocytosis: A Rare Pathology in The Practice of a Pulmonologist. The Russian Archives of Internal Medicine. 2025;15(6):461-467. (In Russ.) https://doi.org/10.20514/2226-6704-2025-15-6-461-467. EDN: FNRNFA

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ISSN 2226-6704 (Print)
ISSN 2411-6564 (Online)