Non-Alcoholic Fatty Liver Disease and Possibilities of Its Therapy (Review)
https://doi.org/10.20514/2226-6704-2026-16-1-20-27
EDN: GEJZGZ
Abstract
NAFLD is an urgent multidisciplinary problem, given its high prevalence worldwide, as well as its role in the development and progression of cardiometabolic disorders and cancer. The review analyzed current data regarding epidemiology, mechanisms of development of non-alcoholic fatty liver disease and current possibilities of its therapy. The problem of NAFLD is well understood. At the same time, new data are published regarding the mechanisms of its development, the impact on other metabolically associated diseases. This proves that a further search for new treatment regimens for such patients is necessary in order to improve the prognosis and reduce cardiometabolic risks. Particular attention in the review was paid to the possibilities of hepatoprotective therapy for hepatic steatosis.
About the Authors
Yu. V. CheremukhinaRussian Federation
Yulia V. Cheremukhina — gastroenterologist, gastroenterology department; Assistant Professor, Department of Therapy and General Medical Practice
Nizhny Novgorod
Competing Interests:
The authors declare no conflict of interests
N. Yu. Borovkova
Russian Federation
Natalya Yu. Borovkova — MD, Professor, First Deputy Director of the Institute of Therapy, Head of the Department of Therapy and General Medical Practice
Nizhny Novgorod
Competing Interests:
The authors declare no conflict of interests
A. S. Vasilkova
Russian Federation
Anastasia S. Vasilkova — MD, PhD, Associate Professor, Department of Hospital Therapy and General Medical Practice
Nizhny Novgorod
Competing Interests:
The authors declare no conflict of interests
O. A. Yermilova
Russian Federation
Olga Aleksandrovna Ermilova, MD, PhD, Deputy Chief Physician for Medical Affairs
Nizhny Novgorod
Competing Interests:
The authors declare no conflict of interests
E. N. Kolodei
Russian Federation
Elena N. Kolodey — MD, PhD, Chief Gastroenterologist of the Nizhny Novgorod Ministry of Health, Head of the Gastroenterology Department
Nizhny Novgorod
Competing Interests:
The authors declare no conflict of interests
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Review
For citations:
Cheremukhina Yu.V., Borovkova N.Yu., Vasilkova A.S., Yermilova O.A., Kolodei E.N. Non-Alcoholic Fatty Liver Disease and Possibilities of Its Therapy (Review). The Russian Archives of Internal Medicine. 2026;16(1):20-27. https://doi.org/10.20514/2226-6704-2026-16-1-20-27. EDN: GEJZGZ
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