ASSESSMENT OF THE DEGREE OF INTOXICATION AND THE FORECAST LEVEL OF THE INTEGRAL INDEX OF INTOXICATION UNDER CERTAIN INFECTIOUS DISEASES
https://doi.org/10.20514/2226-6704-2016-6-2-46-50
Abstract
The Purpose of this research was to study indicators syndrome of endogenous intoxication in patients with erysipelas and herpes infection that can be used to predict relapse in these diseases.
Based on the goal were examined in 54 patients with primary, erythematous form of erysipelas of different localization and 42 patients with the localized form of herpes infection in the dynamics of these diseases.
Determined the level of substances of low and medium molecular weight (HV and SMM), and oligopeptides, as well as the Integral index of intoxication by the method of M. I. Malakhov (1994) and Lowry (1991). To assess the value of the Integral index of intoxication in the prediction of relapses were calculated odds ratio.
Revealed the dependence of studied parameters of disease and completeness of recovery.
Level measurement HV and SMM and oligopeptides allows us to calculate the Integral index of intoxication, which can be used as a prognostic criterion of recurrence as erysipelas, and herpes infection.
About the Authors
M. Y. Marzhokhova
Kabardino-Balkarian State University
Russian Federation
Nalchik
Russian Federation
Nalchik
M. M. Nagoeva
Kabardino-Balkarian State University
Russian Federation
Nalchik
Russian Federation
Nalchik
M. M. Afashagova
Kabardino-Balkarian State University
Russian Federation
Nalchik
Russian Federation
Nalchik
A. R. Marzhokhova
Kabardino-Balkarian State University
Russian Federation
Nalchik
Russian Federation
Nalchik
A. A. Shaova
Kabardino-Balkarian State University
Russian Federation
Nalchik
Russian Federation
Nalchik
References
1. Grebneva O.L., Tkachuk E.A., Czubayko V.O. Method of calculating the percentage of substances of low and medium molecular weight in blood plasma. 2006: 17.
2. Zubovsky, E.T., Kolb V.G. The Syndrome of endogenous intoxication. Health of Belarus. 1994; 4: 60-65.
3. Karyakina E. V., Belova SV. Molecules of average weight as an integral indicator of metabolic disorders (literature review). Clinical laboratory diagnostics. 2004; 3: 4-8.
4. Komarov V.T., Savchenko R.P., Tatarchenko I.P., Prokayeva P.N. Diagnostic value of determination of average weight molecules in infective endocarditis. Clinical laboratory diagnostics. 2001; 8: 19-21.
5. Kopytova T.V., Dobrotin N.A., Khimkina L.N. and all. Laboratory diagnosis of endointoxication in chronic dermatoses. Clinical. Laboratory diagnosis. 2000; 1: 14-17.
6. Malakhova M.Y. Methods of biochemical registration of endogenous intoxication (second message). Efferent therapy. 1995; 1(2): 61-64.
7. Marzhokhova M.Y. Method of registration of endogenous intoxication: a Manual for physicians. St. Petersburg, MAPO.1995; 33 p.
8. Marzhokhova A.R. Dynamics and the integral leukocytic indexes of intoxication when erysipelas. J. Infectious diseases. 2013; 11(Suppl. No. 1 Materials 5-th Annual all-Russian Congress on infectious diseases (Moscow, 25-27 March, 2013): 251.
9. Marzhokhova M.Y., Shaova A.A., Marzhokhova A.R. Development of endotoxemia for certain infectious diseases and methods of its adjustment J. Reports AMAN. 2013; 14(3): 77-80.
10. Medical laboratory technology. Handbook (in 2 volumes). Ed. by A.I. Karpishchenko. St. Petersburg. 1999: 618-647.
11. Mukhamedov I.B., Inoyatova F.I., Aripov O.A., Jolymbetov G. Endotoxemia in chronic viral hepatitis b in children and ways of its reduction. Its main clinical laboratory diagnosis. 2002; 3: 11-13.
12. Lowry O.N. et all. Protein measurement with the Folin reagent. J. Biol. Chem. 1951; 193(1): 265-275.
Review
For citations:
Marzhokhova M.Y., Nagoeva M.M., Afashagova M.M., Marzhokhova A.R., Shaova A.A. ASSESSMENT OF THE DEGREE OF INTOXICATION AND THE FORECAST LEVEL OF THE INTEGRAL INDEX OF INTOXICATION UNDER CERTAIN INFECTIOUS DISEASES. The Russian Archives of Internal Medicine. 2016;6(2):46-50. (In Russ.) https://doi.org/10.20514/2226-6704-2016-6-2-46-50
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