BRUGADA SYNDROME: FROM PRIMARY ELECTRIC HEART DISEASE TO MORPHOLOGICAL SUBSTRATE
https://doi.org/10.20514/2226-6704-2016-6-2-61-69
Abstract
Nowadays interest in channelopathies is growing, and developing diagnostic capabilities make Brugada syndrome much more actual problem than ever. Conception of «primary electric heart disease», which earlier was so popular, now couldn’t explain the absence of single genetic syndromes’ substrate, its’ common combinations with another arrhythmias and the presence of Brugada phenocopy. Conjunction of Brugada syndrome with morphological changes in myocardium , especially myocarditis, is an area of special interest. Infl ammation associates with clinical manifestation of the syndrome, and this situation forces to think about channelopathies’ primacy and to look for another possible mechanisms of Brugada syndrome.
About the Authors
T. A. Pavlenko
First Moscow State Medical University named after I.M. Sechenov
Russian Federation
Russian Federation
6 year, General Medicine,
Moscow
O. V. Blagova
First Moscow State Medical University named after I.M. Sechenov
Russian Federation
Russian Federation
Chair of Internal Medicine № 1,
Moscow
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For citations:
Pavlenko T.A., Blagova O.V. BRUGADA SYNDROME: FROM PRIMARY ELECTRIC HEART DISEASE TO MORPHOLOGICAL SUBSTRATE. The Russian Archives of Internal Medicine. 2016;6(2):61-69. (In Russ.) https://doi.org/10.20514/2226-6704-2016-6-2-61-69
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