MITRAL VALVE PROLAPSE AND SUDDEN CARDIAC DEATH: WHO IS IN THE RISK GROUP?
https://doi.org/10.20514/2226-6704-2016-6-3-25-29
Abstract
Mitral valve prolapse (MVP) is a congenital heart disease, fairly widespread in the population (2-8%). It rarely has complications, but they are serious and include sudden cardiac death (SCD), risk of which rises twofold from 0.2-0.4% cases by MVP. Most deaths are observed among young healthy women. This work is a review of literature dedicated to connection between MVP and SCD designed to explore possible predicts of SCD within patients suffering from MVP and to determine the subset of patients. A conclusion has been made that the connection between MVP and SCD is realized through life-threatening ventricular arrhythmias (VT, VF). The most common site of arrhythmias origin is the inferobasal left ventricular wall. A high-risk subset of patients is determined as young adult women with a midsystolic click at auscultation, bileaflet involvement of the mitral valve, T-wave abnormalities on inferior leads (II, III, aVF) and frequent complex ventricular ectopic activity. Such patients require more intensive disease management of ventricular arrhythmias including consideration of surgical treatment.
About the Authors
O. E. Shirobokikh
Pirogov Russian NationalResearch Medical University
Russian Federation
Moscow
Russian Federation
Moscow
N. A. Bylova
Pirogov Russian NationalResearch Medical University
Russian Federation
Moscow
Russian Federation
Moscow
References
1. Bokeria O.L., Bazarsadaeva T.S. Sudden cardiac death and mitral and aortic valves diseases. Annals arrhythmology. 2013; 10: 162-170.
2. Lectures on cardiovascular surgery. Volume 2 (Edited Bokeria L.A.) M .: A.N. Bakoulev Scientific Center for Cardiovascular Surgery RAMS. 2001; 398.
3. Mazur NA Sudden cardiac death. Medpraktika. M .: 2003 75-77.
4. Nishimura M.D., McGoon M.D. et al. Echocardiographically Documented Mitral-Valve Prolapse — Long-Term Follow-up of 237 Patients. N. Engl. J. Med. 1985; 313: 1305-1309.
5. Narayanan K., Uy-Evanado A., Teodorescu C. et al. Mitral Valve Prolapse and Sudden Cardiac Arrest in the Community, Heart Rhythm. 2015; 13(2): 498-503.
6. Anders S., Said S., Schulz F. Puschel K. Mitral valve prolapse syndrome as cause of sudden death in young adults. Forensic Sci. Int. 2007; 171(2-3): 127-130.
7. Sriram S.C., Syed F.F., Ferguson M.E. et al. Malignant Bileaflet Mitral Valve Prolapse Syndrome in Patients With Otherwise Idiopathic Out-of-Hospital Cardiac Arrest . J. Am. Coll. Cardiol. 2013; 62(3): 222-230.
8. Kligfield P., Levy D., Devereux R.B., Savage D.D. Arrhythmias and sudden death in mitral valve prolapse. Am. Heart. J. 1987; 113: 1298–1307.
9. Lichstein E. Site of origin of ventricular premature beats in patients with mitral valve prolapse. Am. Heart J. 1980; 100: 450–457.
10. Basso C., Marra M.P., Rizzo S. et al. Arrhythmic mitral valve prolapsed and sudden cardiac death. Circulation. 2015; 132: 556–566.
11. Noseworthy P.A., Asirvatham S.J. The Knot That Binds Mitral Valve Prolapse and Sudden Cardiac Death. Circulation. 2015; 132(7): 551-552.
12. Nordhues B.D., Siontis K.C., Scott C.G. et al. Bileaflet mitral valve prolapse and risk of ventricular dysrhythmias and death. Journal of Cardiovascular Electrophysiology. 2016 doi: 10.1111/jce.12914
13. Al-Khatib S.M. The risk of sudden cardiac death in mitral valve prolapse: are all patients created equal? Journal of Cardiovascular Electrophysiology. 2016 doi: 10.1111/jce.12919
Review
For citations:
Shirobokikh O.E., Bylova N.A. MITRAL VALVE PROLAPSE AND SUDDEN CARDIAC DEATH: WHO IS IN THE RISK GROUP? The Russian Archives of Internal Medicine. 2016;6(3):25-29. (In Russ.) https://doi.org/10.20514/2226-6704-2016-6-3-25-29
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