TOWARDS PERSONALIZED TREATMENT OF DEPRESSION
https://doi.org/10.20514/2226-6704-2016-6-4-8-13
Abstract
Disruption of biological rhythms is a relevant factor contributing to the etiology and pathogenesis of depression. This review provides the evidence of desynchronization in the clinical presentation of onset and relapse. The results of own study revealing frequency of sleep disturbances and effects of seasonality on depression risk are presented. According to chronobiology, the current opportunities and promising directions of personalized therapy development are considered.
About the Author
M. Y. Gerasimchuk
Department of psychiatry and narcology, I.M. Sechenov First Moscow State Medical University, Moscow, Russia
Russian Federation
Russian Federation
References
1. Александровский Ю.А. Пограничные психические расстройства: руководство для врачей. М.: ГЭОТАР-Медиа, 2007: 241-262. Aleksandrovskii Y.A. Pogranichnye psikhicheskie rasstroistva [Borderline mental disorders]. Moscow, GEOTAR-Media Publ., 2007: 241-262 (in Russian).
2. Асанов А. О. Нарушения сна при различных типах депрессий (типология, клиника, терапия): автореф. дис. канд.мед.наук: Москва. 2004 Asanov A. O. Narushenija sna pri razlichnyh tipah depressij (tipologija, klinika, terapija): Kand, Diss. [Sleep disturbances in different types of depression (typology, clinic, therapy). Cand. Diss.]. Moskow. 2004 (in Russian).
3. Герасимчук М.Ю. Хронобиологические аспекты депрессии. Клиническая геронтология. 2015; 22(3-4): 61-64 Gerasimchuk M.Y. Depression: a focus on chronobiology. Klinicheskaja gerontologija [Clinical Gerontology]. 2015; 22(3-4): 61-64 (in Russian).
4. Герасимчук М.Ю., Сычев Д.А., Бунятян В.А., Псарева Н.А. Клиническая фармакогенетика антидепрессантов. Ведомости НЦЭСМП. 2013; 2: 15-20. Gerasimchuk M.Y., Sychev D.A., Bunyatyan V.A., Psareva N.A. Pharmacogenetics of antidepressants: clinical aspects. Vedomosti NCJESMP [SCEMAP Bulletin]. 2013; 2: 15-20 (in Russian).
5. Дмитриева Т.Б., Краснов В.Н., Незнанов Н.Г., Семке В.Я., Тиганов А.С. Психиатрия. Национальное руководство. М.: 2009; 490—524. Dmitrieva T.B., Krasnov V.N., Neznanov N.G., Semke V.J., Tiganov A.S. Psikhiatriya: natsional’noe rukovodstvo [Psychiatry: The National Handbook]. Moscow, GEOTAR- Media Publ., 2009; 490–524 (in Russian).
6. Медведев В.Э. Типология сезонных депрессий с учетом особенностей соматовегетативных проявлений. Журнал неврологии и психиатрии им. С.С. Корсакова. 2005;5: 17-22. Medvedev V.E. Somato-autonomic symptoms in different types of seasonal affective disorders. Zh Nevrol Psikhiatr Im S S Korsakova. 2005; 105(5): 17-22 (in Russian).
7. Мосолов С.Н. Биологические методы терапии психических расстройств (доказательная медицина — клинической практике). М.: Социально-политическая мысль, 2012: 1076 Mosolov S.N. Biologicheskie metody terapii psihicheskih rasstrojstv (dokazatel’naja medicina — klinicheskoj praktike [Biological therapies of mental disorders (evidence-based medicine for clinical practice)]. Moscow, Social’no-politicheskaja mysl’ Publ., 2012: 1076 p. (in Russian).
8. Оганов Р.Г., Ольбинская Л.И., Смулевич А.Б. Депрессия и расстройства депрессивного спектра в общемедицинской практике. Результаты программы КОМПАС. Кардиология. 2004; 1: 48–55. Oganov R.G., Ol’binskaya L.I., Smulevich A.B., Drobizhev M.J., Shal’nova S.A., Pogosova G.V. Depression and depressive disorders in general medical practice. The results of the Kompas program. Kardiologiya [Сardiology], 2004, no. 1, 48-55 (in Russian).
9. Осканова Р.С., Ильченко Л.Ю., Луговкина Е.А. Опыт применения псиллиума в лечении печеночной энцефалопатии у больных с хроническими заболеваниями печени. Архивъ внутренней медицины. 2012; 5:18-25 Oskanova R.S., Il’chenko L.J., Lugovkina E.A., Fedorov I.G., Mel’nikova L.I., Storozhakov G.I. Psyllium using in chronic liver diseases and hepatic encephalopathy. Arhiv vnutrennej mediciny [Archive of internal medicine], 2012, no. 5, pp. 19-25 (in Russian). DOI:10.20514/2226-6704-2012-0-5-19-25
10. Ротштейн В.Г., Богдан М.Н., Долгов С.А. Эпидемиология депрессий. В кн.: Депрессия и коморбидные расстройства. Под ред. А.Б. Смулевича. М: Медицина 1997; 138-164. Rotshtejn V.G., Bogdan M.N., Dolgov S.A. Jepidemiologija depressij. Depressija i komorbidnye rasstrojstva. Pod red. A.B. Smulevicha. [Epidemiology of depression. Depressions and Comorbid Disorders. Ed. by A.B.Smulevich].Moscow: Medicina 1997; 138-164 (in Russian).
11. Снежневский А.В. Клиническая психопатология. Руководство по психиатрии. М.: Медицина, 1983:16–98. Snezhnevskij A.V. Klinicheskaja psihopatologija. Rukovodstvo po psihiatrii [Clinical psychopathology. Guide to psychiatry]. Moscow, Medicina Publ., 1983. pp. 16-98 (in Russian).
12. Хильдебрандт Г., Мозер М., Лехофер М. Хронобиология и хрономедицина. М.: Арнебия. 2006: 144с. Hildebrandt G., Moser M., Lehofer M. Chronobiologie und Chronomedizin: biologische rhythmen — medizinische konsequenzen. Stuttgart, Hippokrates Publ., 1998, 141 p. (Russ. ed.: Hil’debrandt G., Mozer M., Lehofer M. Hronobiologija i hronomedicina. Moscow, Arnebija Publ., 2006. 144 p.)
13. 5th ed. Arlington: American Psychiatric Association; 2013. American Psychiatric Association: Diagnostic and Statistical Manual of Mental Disorders.
14. Becker-Krail D., McClung C. Implications of circadian rhythm and stress in addiction vulnerability. F1000Research. 2016; 13(5):59.
15. Benedetti F., Barbini B., Colombo C. et al. Chronotherapeutics in a psychiatric ward. Sleep Medicine Reviews. 2007; 11: 509–522.
16. Berdynaj D., Boudissa S.N., Grieg M.S. et al. Effect of chronotype on emotional processing and risk taking. Chronobiol Int. 2016; 33(4): 406-18.
17. Borbely A.A. A two process model of sleep regulation. Human Neurobiology.1982; 1(3):195-204.
18. Droit-Volet S. Time perception, emotions and mood disorders. Journal of Physiology-Paris. 2013; 10: 255–264.
19. Duval F., Mokrani M.C., Erb A. et al. Chronobiological hypothalamic–pituitary–thyroid axis status and antidepressant outcome in major depression. Psychoneuroendocrinology. 2015; 59: 71-80.
20. Ford D.E., Kamerow D.B. Epidemiological study of sleep disturbances and psychiatric disorders. An opportunity for prevention? JAMA.1989; 262: 1479-1484.
21. Gerasimchuk M.J. Comprehensive and integrated assessment of patients with depression. Abstr. 16th ESDAP International Congress. Acta Dermato-Venereologica. Saint-Petersburg, 2015; 95, pp. 28-29
22. Guaiana G., Gupta S., Chiodo D. et al. Agomelatine versus other antidepressive agents for major depression. Cochrane Database of Systematic Reviews. 2013, Issue 12.
23. Gubin D.G., Weinert D. Deterioration of temporal order and circadian disruption with age 2: Systemic mechanisms of agingrelated circadian disruption and approaches to its correction. Advances in Gerontol. 2016; 6 (1): 10-20
24. Grüter W., Pöldinger W. Maprotiline. Mod Probl Pharmacopsychiatry. 1982; 18: 17-48.
25. Halberg F. Chronobiology. Annu. Rev. Physiol., 1969; 31: 675–725
26. Iitaka C., Miyazaki K. et al. A role for glycogen synthase kinase-3beta in the 41 mammalian circadian clock. J Biol Chem 2005; 280: 29397-402.
27. Keller K.L., Zöschg S., Grünewald B. Chronotype and depression in adolescents — a review. Kinder Z Jugendpsychiatr Psychother.2016; 44 (2): 113-26.
28. Kraepelin E., Fleck U. Ueber die Tagesschwankungen bei Manisch-Depressiven. Psychologische Arbeiten. 1922; 7: 213-353.
29. Lee H.-J., Son G.-H., Geum D. Circadian Rhythm Hypotheses of Mixed Features, Antidepressant Treatment Resistance, and Manic Switching in Bipolar Disorder. Psychiatry Investig. 2013; 10 (3): 225-32.
30. Leopolda K., Reifb A., Haacka S. et al. Type 2 diabetes and prediabetic abnormalities in patients with bipolar disorders.J Affect Disord.2016; 189: 240-5.
31. Liira J., Verbeek J., Ruotsalainen J. Pharmacological Interventions for Sleepiness and Sleep Disturbances Caused by Shift Work. JAMA.2015; 313(9): 961-962.
32. Madrid-Navarro C.J., Sanchez-Galvez R., Martinez-Nicolas A. et al. Disruption of circadian rhythms and delirium, sleep impairment and sepsis in critically ill patients. Potential therapeutic implications for increased light-dark contrast and melatonin therapy in an ICU environment. Curr Pham. 2016; 21(24): 3453-3468.
33. Nierenberg A.A., Keefe B.R., Leslie V.C. et al. Residual symptoms in depressed patients who respond acutely to fluoxetine. J Clin Psychiat.1999; 60: 221-225.
34. Papousek M. Chronobiologishe aspekte der zyklothymie. Fortsch. Neurol.Psychiatre.1975; 43: 381-440
35. Summa K.C., Turek F.W. The Clocks within Us. Scientific American. 2015; 312 (2): 50-55.
36. Tseng P.T., Chen Y.W., Tu K.Y. et al. Light therapy in the treatment of patients with bipolar depression: A meta-analytic study. Eur Neuropsychopharmacol. 2016. doi: 10.1016/j.euroneuro.2016.03.001.
Review
For citations:
Gerasimchuk M.Y. TOWARDS PERSONALIZED TREATMENT OF DEPRESSION. The Russian Archives of Internal Medicine. 2016;6(4):8-13. (In Russ.) https://doi.org/10.20514/2226-6704-2016-6-4-8-13
Views:
1160
Email this article 