THE EFFECT OF INTERVAL NORMOBARIC HYPOXIC TRAINING ON QUALITY OF LIFE AND PSYCHO-VEGETATIVE STATUS OF PATIENTS WITH ESSENTIAL HYPERTENSION WITH METABOLIC SYNDROME

Objective: to clarify the dynamics of quality of life and psycho-autonomic profi le of patients with hypertension in combination with metabolic syndrome, with the use of interval normobaric hypoxic training. Materials and methods: examined 104 patients with essential hypertension stage I — III, 1 — 3 degrees on the background of metabolic syndrome, the average age 48,29±2.23 years. The observation group (54 patients) received a course of interval normobaric hypoxic training on the background of pharmaco- and diet therapy. The comparison group (50 patients) received drug therapy and diet therapy. Quality of life was assessed by SF-36 questionnaire (Russian version), psychological status scale CESD depression, vegetative disorders — according to the “Questionnaire to identify signs of vegetative changes Wayne”. The studied parameters were determined at baseline, after 1 and 6 months from initiation of therapy. Results: the dynamic monitoring of the surveyed showed positive changes in the clinical picture of the disease in both groups in the normalization of blood pressure, reduction of body mass index, more pronounced in patients of the observation group. The application course of interval normobaric hypoxic training provided signifi cantly earlier and more pronounced dynamics of quality of life, reducing the severity of depressive and vegetative disorders in patients. Conclusion: the course of interval normobaric hypoxic training in patients with essential hypertension and metabolic syndrome on the background of drug treatment provides the positive dynamics of quality of life, psychological and vegetative indices, exceeding the effi ciency of isolated pharmacological treatment. The estimation of these parameters can serve as an additional criterion in assessing the therapeutic effect of antihypertensive treatment.

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