PULMONARY AND LIVER DAMAGE DURING TREATMENT WITH ACETAMINOPHEN (PARACETAMOL)
https://doi.org/10.20514/2226-6704-2016-6-4-58-64
Abstract
This is a case report of pulmonary damage in the form of intestinal pneumonitis with severe respiratory failure during administration of acetaminophen (paracetamol). In addition, significant increase of ALT and AST levels without clinical signs of liver damage was observed in this patient. After glucocorticoids administration regression of radiological abnormal findings in the lungs along with normalization of liver enzymes values were registered. The rarity of interstitial pneumonitis induced by acetaminophen (paracetamol), especially in combination with liver damage, is emphasized. The presented patient history is the first case report of drug-induced hepatopulmonary syndrome during acetaminophen (paracetamol) administration.
About the Authors
L. I. Dvoretski
The First Moscow State Medical University n. I.M. Sechenov, Moscow, Russia
City Clinical Hospital n. S.S. Yudin, DHM, Moscow, Russia
Russian Federation
Russian Federation
A. N. Kovalevskaja
The First Moscow State Medical University n. I.M. Sechenov, Moscow, Russia
City Clinical Hospital n. S.S. Yudin, DHM, Moscow, Russia
Russian Federation
Russian Federation
S. E. Kolendo
The First Moscow State Medical University n. I.M. Sechenov, Moscow, Russia
City Clinical Hospital n. S.S. Yudin, DHM, Moscow, Russia
Russian Federation
Russian Federation
E. V. Sergeeva
The First Moscow State Medical University n. I.M. Sechenov, Moscow, Russia
City Clinical Hospital n. S.S. Yudin, DHM, Moscow, Russia
Russian Federation
Russian Federation
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Review
For citations:
Dvoretski L.I., Kovalevskaja A.N., Kolendo S.E., Sergeeva E.V. PULMONARY AND LIVER DAMAGE DURING TREATMENT WITH ACETAMINOPHEN (PARACETAMOL). The Russian Archives of Internal Medicine. 2016;6(4):58-64. (In Russ.) https://doi.org/10.20514/2226-6704-2016-6-4-58-64
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