Early diagnosis and early initiation of adequate therapy in the spectrum of anxiety disorders (AD) is one of the pressing problems of modern medicine, which is determined by the high prevalence and significant impact on quality of life of AD is not only burdened with somatic patients, but also physically healthy people. The article deals with aspects of diagnosis and treatment of TS in the general medical network, in particular, describes the currently recommended regimen of the drug Phenorelaxan and benefits of this drug.

The investigation of prescribing to patients with myocardial infarction in the recommendations on discharge from hospital and outpatient was provided. Patients were studied by polling performance of medical prescriptions; found the average level of compliance. The reasons for low compliance were: forgetfulness, lack of pain, medication “on demand”, long term after myocardial infarction. The factors of compliance to treatment: female, recent months after a heart attack, the credibility to the doctor, a high level of medical and social awareness, the absence of bad habits.

Changing of the structural and functional state of the left ventricle (LV) heart objectively describes his defeat in arterial hypertension (AH). However, the features of changes of LV in patients with renal hypertension currently remain unstudied. The target of our work was to study the structural and functional features of the left ventricle of the heart in patients with renal hypertension without signs of kidney failure.  Echodopplercardiography of structural and functional parameters of left ventricular heart disease was applied in 136 patients with hypertensive form of chronic glomerulonephritis. The study showed that patients with renal hypertension without signs of kidney failure, ranging from grade 2 hypertensive syndrome, LV hypertrophy develops. At the same time in individuals with grade 2 hypertension it is formed by concentric, while grade 3 hypertension, as dilated eccentric. At the same time, with grade 2 and moreover grade 3 items in hypertension systolic LV function was reduced. Diastolic LV dysfunction was diagnosed in all patients with renal hypertension.

In article importance of timely diagnostics and treatment of a chronic pyelonephritis is underlined. The text contains results of researches with using electrochemical activated water solutions in complex therapy of chronic pyelonephritis at a stationary and out-patient stage. These solutions can accelerate recovery and increase remission term at patients. Authors investigated a condition of free-radical oxidation and level antioxidant protection at patients with chronic pyelonephritis for studying mechanism of action electrochemical activated water solutions in the given pathology.

Acute cerebral blood flow disturbances now are the most important medical and social problem. They become a major cause of permanent loss of disability. Given the rising incidence of stroke in working age, it certainly is important. Use of cytoprotector in the treatment of patients with ischemic stroke leads to a statistically significant decrease of neurological deficit, improvement of social and domestic adaptation levels and quality of life. The authors present the results of their own clinical research on the effectiveness of the drug Mexicor® in patients with acute ischemic stroke.

The purpose of our research was to study features of development of dyssynchrony in patients with heart failure and different forms of ischemic heart disease, and also to estimate efficiency of cardiac resynchronization therapy. 125 patients with ischemic heart failure (including 17 patients, who were studied prior and within 1 week after biventricular pacing) were studied. Frequency of revealing dyssynchrony is connected with presence at patients an aberrant cardiac rhythm. After biventricular pacing we found significant positive dynamics of clinical and echocardiographic parameters in patients with heart failure.

In the pathogenesis of renal arterial hypertension an important role of the renin-angiotensin-aldosterone (RAAS) is confirmed. In addition to the humoral effects of the RAAS and blood pressure actively controls the vegetative nervous system (VNS). However, the state of VNS in renal hypertension remains little studied. We examined 130 patients with chronic glomerulonephritis and secure renal function (100 hypertensive and 30 normotensive). As the weighting of the hypertensive syndrome in patients with renal hypertension is a reduction in autonomic effects on the cardiovascular system with a simultaneous increase in the level of active renin and aldosterone content.

Transesophageal electric stimulation (TES) is a method of non-invasive cardiac electrophysiology studies. The aim of the study is to evaluate the possibility of TES in the research into atrio-nodal conductions. The scientific innovation is in a non-invasive analysis of the heterogeneity of the refractory period of atrio-nodal connections. 249 patients were examined. By the nature of AV-conduction curve the patients were divided into 2 groups. The first group (109 persons) consisted of the patients with diagnosed transition point (TP). The second group included 140 people, whose V1-V2 dependence of A1-A2 was close to a line — without a TP. It was discovered that the differences in atrio-nodal conductions depend on the effective refractory period of atrioventricular connection. A low index of ERP atrio-nodal conduction is more physiological and accompanied (ERP) by the absence of the increase heart rate under the most further increase the frequency atrial stimulation. A high index of ERP can be caused by different reasons. This variant of atrio-nodal conductions is followed by less favorable changes in hemodynamics.

Electric and viscoelastic parameters of erythrocytes in patients with diffuse liver diseases with different stages and genesis and healthy men were studied by dielectrophoresis. The lowest strain amplitude of erythrocytes, tendency to aggregation, destruction, low resistance, high electrical conductivity of the membranes had thickened red blood cells of patients with mixed etiology of the process, changes were compounded from stage of hepatitis to cirrhosis (p < 0,05). In alcoholic liver disease revealed the greatest differences in the levels of strain amplitude of erythrocytes, polarizability, dipole moment, index of destruction compared to the viral etiology. Chronic HCV-infection leads to large shifts in the parameters of erythrocytes in comparison with HBV (p < 0,001–0,05). Parameters of erythrocytes can be used as an additional criterion for the differential diagnosis, prognosis of the disease, making additional emphasis in the treatment.

The article presents the results of examination of patients with chronic abdominal ischemia with hemodynamically significant unpaired visceral branches of the abdominal aorta lesion. Functional classes of chronic abdominal ischemia are defined. It allows to estimate clearly the disease progress in patients with intravazal and extravasal stenosis and to justify further treatment strategy.

Performance analysis of the therapeutic services of the Volga Federal District (VFD) shows gradual reduction of the population mortality. But there are still relevant issues to reduce the abundance and mortality due to diseases of the cardiovascular system, including a first coronary heart disease, hypertonic disease and chronic heart failure. Widespread respiratory diseases, diseases of endocrine system (asthma, diabetes, etc.) require no less attention of VFD therapeutic services. All this determines the importance of preventive measures and control of modifiable risk factors of disease. Current rate is for the early identification of therapeutic pathology.